HOUSTON, September 15, 2023 (Newswire.com)
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Over the last few years, the landscape of plastic surgery has seen remarkable changes. Dr. Robert Kratschmer, a board-certified plastic surgeon based in Houston, sheds light on how the popularization of the drug Semaglutide is affecting patient choices in cosmetic procedures.
"Two years ago, liposuction and fat transfer were the procedures that dominated patient interest," says Dr. Kratschmer. "While they remain popular, the rise of Semaglutide for weight management has led to a notable increase in other procedures, like panniculectomy, thigh lift, arm lift, and neck lift surgeries."
Semaglutide, originally developed for the treatment of type 2 diabetes, has been growing in prominence for its off-label use in weight management. This has had ripple effects in the plastic surgery community.
Dr. Kratschmer explains, "Semaglutide has offered a non-surgical option for weight loss, which is changing the kinds of procedures people are seeking. Many of my patients have successfully used it for weight loss, but are then left with excess skin that they want to address. As a result, we're seeing a considerable uptick in surgeries designed to remove excess skin and contour the body."
This shift is significant, not only for prospective patients but also for the medical community at large. The rising interest in these procedures suggests that people are becoming increasingly conscious of comprehensive body transformations that focus on both weight loss and body contouring.
"Every medical advancement impacts patient choices," Dr. Kratschmer says. "As physicians, we must adapt and continue to offer the best care based on emerging trends and technologies. It's an exciting time in the field of plastic surgery, and I'm eager to see how this evolves in the years to come."
For those considering plastic surgery, Dr. Kratschmer advises consultations to discuss individual needs and options. "Patient care is always our utmost priority. Our consultations aim to guide patients through the variety of choices now available, so they can make informed decisions that align with their goals," he concludes.
To learn more about Dr. Robert Kratschmer and his practice, please visit SiliconeMD.com.
About Dr. Robert Kratschmer
Dr. Robert Kratschmer is a board-certified plastic surgeon with over 20 years of experience. Based in the Greater Houston area, he specializes in a wide range of cosmetic procedures and is committed to providing exceptional care for his patients.
Contact Information:
Amber K.
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As published in the journal Food and Chemical Toxicology, the biopharmaceutical drug development firm's sponsored research used co-cultured human, primary immune cells as a model to evaluate the ability of selected Cannabis constituents to decrease inflammation.
Gb Sciences, Inc. (OTCQB:GBLX), a leading plant-inspired, biopharmaceutical research and drug development company, has co-published a study in the journal Food and Chemical Toxicologythat demonstrates the potential of selected cannabinoids and terpenes to reduce inflammation. Finding Cannabis compounds with anti-inflammatory properties may be useful in decreasing inflammation associated with a wide range of serious human disorders, and these Cannabis compounds potentially have more favorable side effect profiles than NSAIDs (Non-Steroidal Anti-Inflammatory Drugs), which currently lead the anti-inflammatory market based on sales. Largely because of the increasing prevalence of chronic and auto-immune inflammatory disorders, the market for anti-inflammatory therapies is expected to grow to $191.42 billion by 2027.
"We believe that this is the first demonstration of the anti-inflammatory potential of some very potent minor cannabinoids and terpenes derived from Cannabis," said Dr. Andrea Small-Howard, President, Chief Science Officer, and Director of Gb Sciences. "The identification of cell type-specific immune modulating effects by different individual cannabinoids and terpenes was an important first step in designing our novel anti-inflammatory therapies. The results from our second study on the anti-inflammatory effects of proprietary mixtures of these ingredients will be published subsequently with our collaborators at Michigan State University and Chaminade University."
Gb Sciences selected the specific Cannabis constituents for this study based on their prior activity within chemovar studies. To determine whether these cannabinoids and terpenes could reduce inflammation, Gb Sciences' colleagues at Michigan State University tested the individual Cannabis constituents over a wide range of concentrations in human, primary immune cells in a co-culture system that mimics the complex interactions that regulate the human immune system. Three immune cell types were chosen as representatives within these native human immune cell mixtures based on their important roles in modulating the inflammatory cascade.
This study demonstrated that delta-9 tetrahydrocannabinol (THC) had the greatest effect on reducing inflammatory biomarkers and processes in all three immune cell types. Following THC, the greatest immune activity modulation was measured by cannabidivarin (CBDV), cannabigerol (CBG), cannabichromene (CBC), cannabinol (CBN), and lastly, cannabidiol (CBD) in decreasing order based on the number of statistically significant changes measured in inflammatory bioassays relative to the control. Some of these minor cannabinoids and the terpenes tested had very 'selective' anti-inflammatory effects, which targeted a single cell type and/or caused a change in only a single inflammatory bioassay.
This study entitled "Evaluation of the anti-inflammatory effects of selected cannabinoids and terpenes from Cannabis Sativa employing human primary leukocytes" was co-authored by Gb Sciences' own President and Chief Science Officer, Andrea Small-Howard, and her collaborators Lance K. Blevins, Anthony P. Bach, Robert B. Crawford, Jiajun Zhou, Joseph E. Henriquez, Michael D. Rizzo, Sera Sermet, D.M. Isha Olive Khan, and Norbert Kaminski from Michigan State University (East Lansing, Michigan, USA) and Helen Turner from Chaminade University of Honolulu (Honolulu, Hawai'i, USA). The second part of this study measured the effects of proprietary mixtures of cannabinoids and terpenes on inflammation within this human, primary immune cell model, and this second study will be published next in collaboration with our colleagues at Michigan State University and Chaminade University.
Gb Sciences, Inc. is a plant-inspired, biopharmaceutical research and development company creating patented, disease-targeted formulations of cannabis- and other plant-inspired therapeutic mixtures for the prescription drug market through its Canadian subsidiary, GbS Global Biopharma, Inc. The 'plant-inspired' active ingredients in its therapeutic mixtures are synthetic homologues identical to the original plant compounds but produced under current Good Manufacturing Practices. Gb Sciences' intellectual property portfolio contains six issued U.S. and three issued foreign patents, as well as 17 U.S. and 51 foreign patent-pending applications. In its drug development pipeline, Gb Sciences has five preclinical phase product development programs. Gb Sciences' lead program for Parkinson's disease is being prepared for a first-in-human clinical trial. Gb Sciences' formulations for chronic pain, anxiety, and depression are currently in preclinical animal studies with researchers at the National Research Council of Canada. The company also received positive preclinical proof-of-concept data supporting its complex mixtures for the treatment of Cytokine Release Syndrome related to COVID-19, and its lead candidates will be optimized based on late-stage preclinical studies at Michigan State University. Gb Sciences' productive research and development network includes distinguished universities, hospitals, and Contract Research Organizations. To learn more, visit www.gbsciences.com.
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