TOKYO, June 20, 2023 (Newswire.com)
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Hotel Chinzanso Tokyo announces its summer-long event, the Ultimate Sea of Clouds, launching Monday, July 3rd. Visitors can take a break from the summer heat and refresh in the hotel's traditional Japanese garden, where the award-winning Tokyo Sea of Clouds will have twice the amount of mist as usual.
The Tokyo Sea of Clouds debuted in 2020 as part of the first phase of the hotel's Garden Project, a series of projects created to celebrate the hotel's 70th anniversary. In 2023, it made its mark globally when the "Tokyo Sea of Clouds and the Seven Seasons" won the Urban/Landscape Architecture category of the iF Design Awards, one of the world's oldest and most prestigious design awards.
At regular intervals throughout the day, the entire garden is shrouded in mist, creating an effect that is usually only seen from mountaintops under certain weather conditions. The sea of clouds is such a rare view that it is considered a miracle to witness it even once. With double the amount of mist, this summer's Ultimate Sea of Clouds takes it up a notch, making the garden even more alive and dynamic than usual.
Also on display from July 3rd is 'wind chime alley,' where approximately 300 Edo-style wind chimes will be arranged along a pathway in the garden, immersing guests in the sounds of summer. In addition, the hotel is hosting a competition where Ultimate Sea of Clouds-themed sweets will go head-to-head in a friendly battle.
The hotel is also preparing a special dessert for the occasion. The Lemon Tokyo Sea of Clouds Zuccotto comprises a ricotta cheese-based cassata cream that is wrapped in a fluffy white sponge, topped with cloud-like Chantilly cream, and finished with powdered sugar. It is available for purchase at the hotel shop or as part of the dinner course at Il Teatro.
You can see more information about the Ultimate Sea of Clouds and related events on the hotel website or on their YouTube channel.
About Hotel Chinzanso Tokyo
Hotel Chinzanso Tokyo is one of the city's most iconic luxury hotels with 70 years of history. The property includes 267 guest rooms/suites, nine restaurants, 38 meeting/banquet rooms, and a full-service spa with a Japanese onsen. Its award-winning garden has a wide variety of botanicals, including more than 100 cherry trees and 1,000 camellia trees. The standout feature of the garden is the 'Tokyo sea of clouds,' a recreation of the natural phenomenon that can usually only be found in the mountainous regions of Japan. The hotel is owned and managed by Fujita Kanko Inc., a publicly-traded tourism industry corporation headquartered in Tokyo.
Unannounced Meal Management Efficacy Key to a Better Quality of Life for People with Diabetes
BERLIN, February 23, 2023 (Newswire.com)
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At the International Conference on Advanced Technologies & Treatments for Diabetes, Diabeloop, a leader in Automated Insulin Delivery technology, announces the launch of a clinical study in adolescents and young adults with T1D, in France, Belgium and Germany. The main objective is the validation of its hybrid closed-loop system that doesn't require meal declarations, a major step towards fully automated solutions.
Major impact on quality of life expected
The open-label, multicenter, randomized, cross-over, four-week outpatient study1 will assess, in real-life conditions, the efficacy of Diabeloop's integrated solution, embarking an Unannounced Meal Management module.
The Automated Insulin Delivery system will also integrate Terumo Corporation's MEDISAFE WITH patch pump, for the first time since the companies announced extended development and commercial agreements a little over a year ago.
The wearable, lightweight patch pump will optimize comfort for the 50 adolescents and young adults with T1D, aged from 12 to 18 years old, enrolled in this study.
Three reference hospitals in France, Belgium and Germany are involved in the trial, whose inclusion phase should be completed by the end of March:
Necker-Enfants Malades Hospital, Paris, France, Department of Endocrinology, Diabetes and Nutrition led by Prof. Jacques Beltrand, Principal Investigator of the study
Catholic University, Leuven, Belgium, Pediatric Endocrinology Unit, Prof. Kristina Casteels
Kinder-und Jugendkrankenhaus, Hannover, Germany, Diabetes Center for Children and Adolescents Auf Der Bult, of Prof. Thomas Danne
"The Diabetes Center AUF DER BULT treats close to 800 youth with type 1 diabetes. Devices for diabetes technology are now a standard at our center. Nevertheless, for many adolescents, it remains a burden to enter carb counts even during automated insulin therapy. We are eager to study new approaches to reduce this burden in our clinical research center like this international collaborative study in adolescents and young adults," declares Prof. Thomas Danne.
An answer to patients' needs, driven by scientific observations
More than a mission, patient knowledge is intrinsic to Diabeloop. Therefore, the company understands the increased complexity of insulin management during adolescence; families constantly report difficulties at school and the influence of the social environment on disease acceptance, for example.
Together with their partner CEA-Leti, Diabeloop confirmed and refined the understanding of the unmet need with a workshop: people with diabetes shared their experience of managing diabetes during their teenage years. The burden of diabetes management and the impact of forgetting to bolus were some of the main concerns shared by the participants.
Those experiences very much support the scientific conclusions that led Diabeloop to develop the project of the study, focused on meal management, for 12- to 18-year-old patients.
A study2 indeed showed that only 17% of young patients achieved the HbA1c goal of 3 looked at the effect of missed meal boluses, concluding that "four missed meal boluses per week can result in a 1% increase in HbA1c" while observing that "it is likely that many missed boluses occur in social settings".
While beneficial to all, a fully closed-loop with Unannounced Meal functionality would have a major impact on quality of life for the younger population, who are also prone to be early adopters of new technologies and patch pumps.
Unannounced Meal Management: more automation, more personalization
The Unannounced Meal Management (UMM) module is directly embedded in Diabeloop's self-learning algorithm.
The UMM feature is automatically activated when the algorithm detects a significant blood glucose rise, associated with a high probability that a meal triggered this spike in glucose levels.
UMM enables patients to not declare a meal. Diabeloop's algorithm will detect an unexpected high and correct it by adjusting insulin doses. Combined with its unique auto-learning capacities - optimizing, among others, the meal ratio incrementally - this innovation contributes to feeding Diabeloop's holistic approach, considering the singularities and the personal needs of every individual.
Erik Huneker, CEO and co-founder of Diabeloop, comments: "Every person with diabetes is unique and deserves solutions that will adapt to his or her physiology and lifestyle. That's why a high level of personalization truly matters. There is still some way towards true fully closed-loop solutions but the integration of the UMM module would be a very significant milestone. The efficacy of the UMM will be firstly assessed in adolescents and young adults with diabetes, who profoundly need this major improvement, but it will be generalized and implemented in all of Diabeloop's AID solutions in the near future".
The development of the Unannounced Meal Management (UMM) and the design of the clinical study for T1D adolescents and young adults have been supported by funding from EIT Health and the consortium members.4
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About Diabeloop
Diabeloop's mission: Making innovation accessible to people living with diabetes, improving clinical results while relieving them of their constant mental burden.
Created in 2015, Diabeloop offers AI-based, personalized solutions to improve clinical outcomes for people with diabetes while relieving them of their constant mental burden. DBLG1 System, Diabeloop's first medical device for automated insulin delivery (AID) and DBL-hu, its solution for highly unstable Type 1 diabetes management, are both CE-marked and being deployed in Europe.
Diabeloop completed its Series C financing round in June 2022, securing 70 million euros to accelerate its commercial roll-out and support its sustained growth strategy and its high-impact projects.
Today, Diabeloop gathers the personality, passion, and skills of talented individuals who work hard to improve the quality of life for every person living with diabetes.
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References:
1 NCT04725591
2 Miller KM Diabetes Care 2015;38:971-978 "The American Diabetes Association (ADA) HbA1c goal of
3 Pediatr Diabetes. 2010 Nov; 11(7): 498-504. Comeaux SJ, Jaser SS. Autonomy and insulin in adolescents with type 1 diabetes.
4 CEA-Leti, CERITD, RI.SE, Profil, KU LEUVEN.
Contact Information:
Stéphanie JÉGU
Global Brand & Communication Director, Diabeloop [email protected]
