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CARDIO inCode Study Results Presented at ESC Annual Meeting

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CARDIO inCode Study Results Presented at ESC Annual Meeting
Coronary Heart Disease (CHD) prevention nearly twice as effective when using CARDIO inCode as method to target treatment

GENinCode Plc (AIM - GENI), the polygenics company focused on the prevention of cardiovascular disease, announced the presentation by Kaiser Permanente on the 'Utility of the CARDIO inCode-Score CHD polygenic risk score for incident coronary heart disease interplay with lifestyle in a multi-ethnic cohort of more than 60,000 individuals.' The presentation was made at the Annual Meeting of the European Society of Cardiologists ("ESC") Congress from August 25-28, 2023 in Amsterdam.

The study found that genetic and lifestyle factors are independently associated with the incidence of Coronary Heart Disease ("CHD") and for individuals with a high polygenic risk measured by CARDIO inCode-Score ("CIC-SCORE"), a favourable lifestyle was associated with a 52% lower rate of CHD compared with an unfavourable lifestyle. The study also found that CIC-SCORE can identify individuals at the highest risk of CHD. These individuals should then be prioritised for lifestyle advice and where appropriate, therapeutic intervention as they will benefit most. CIC-SCORE is a first-in-class commercially available in-vitro diagnostic test used to assess an individual's polygenic risk of CHD.

By stratifying patients based on their polygenic risk score and targeting treatment to those with the highest risk score, the 'numbers needed to treat' (NNT) to prevent a CHD event were almost halved (CHD 'event' includes: non-fatal AMI, angina and coronary revascularisation procedures (coronary by-pass or percutaneous intervention) or CHD death). CHD prevention was nearly twice as effective when using CIC-SCORE as a method to target treatment. The study also confirmed the earlier in life preventative measures can be put in place, the lower the future risk underlining the need for polygenic risk score lifetime risk assessment to be used in conjunction with traditional clinical risk assessment.

The study investigated over 60,000 adult individuals with no history of CHD from the Genetic Epidemiology Resource in Adult Health and Aging ("GERA") multi-ethnic cohort of the Kaiser Permanente Medical Care plan of Northern California, USA. The GERA cohort followed the membership over an average of 14 years, using CIC-SCORE to assess the polygenic risk of CHD, interplay with lifestyle and the incidence of CHD. See the notes for more details on CIC-SCORE

Heart and circulatory disease, also known as cardiovascular disease (CVD), is the leading cause of death globally, taking an estimated 17.9 million lives each year, with Coronary Heart Disease representing the leading cause of death for men, women, and people of most racial and ethnic groups in the United States.

Matthew Walls, CEO of GENinCode PLC, said: "We are delighted with the results demonstrating use of CIC-SCORE as part of targeted treatment for CHD prevention was nearly twice as effective. The ESC presentation is the first of a number of publications showing the clinical utility of CIC-SCORE (polygenic risk score) to identify individuals at high genetic risk of coronary heart disease, thereby enabling targeted, personalised treatment and a breakthrough in preventive care."

For more information, visit www.genincode.com.

CIC-SCORE is a commercially available polygenic test from the GENinCode CAP-accredited laboratories based in Irvine, California. The test is based on published clinical evidence amassed over 15 years which, combined with traditional clinical risk factors, provides a comprehensive risk assessment (clinical + genetic) of CHD for use in primary preventive care. GENinCode labs process patient DNA samples and deliver test results to physicians via an online cloud-based algorithmic reporting system ('SITAB'). The test is also advancing with the FDA for approval. 

Contact Information:
Matthew Walls
CEO
[email protected]
00447887501998


Original Source: CARDIO inCode Study Results Presented at ESC Annual Meeting

Caregiver Thrive, Learn & Connect Support Program Enriches the Lives of Family Caregivers in North Carolina

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Caregiver Thrive, Learn & Connect Support Program  Enriches the Lives of Family Caregivers in North Carolina

Dr. Julian Montoro-Rodriguez

Principle Investigator\nUNC Charlotte

After receiving widespread attention for demonstrating positive outcomes in Charlotte and other parts of North Carolina, the Caregiver Thrive, Learn, Connect (TLC) Program is set to make significant strides in supporting caregivers across the country. The program's remarkable success comes at a crucial time. Fifty-three million adults in the U.S. (21.3 percent) are caregivers, but access to affordable and coordinated services remains scarce.

Structured for Success

The research phase of the program, spearheaded by UNC Charlotte and supported by generous funding from Southminster, began in the Charlotte area in Spring 2021 and released findings in Summer 2023. It offered free online workshops and support to adults providing care to people with memory loss, dementia, or chronic illness. Caregivers completed six weekly sessions led by trained facilitators through video conferencing. The workshops were designed to teach coping skills caregivers need to deal with stress, depression and burden, as well as strategies to improve quality of life.

Background

It took years of dedicated bi-coastal collaboration to develop and test the efficacy of the program with a goal of making it free and accessible for anyone caring for a loved one with a chronic condition or significant memory impairment. 

--Dr. Dolores Gallagher-Thompson, Stanford University, developed the original program called Coping with Caregiving about 20 years ago. The program was successfully offered to individual and small groups of caregivers in person. 

--Principal Investigator Dr. Julian Montoro-Rodriguez at UNC Charlotte adapted the Coping with Caregiving program to be delivered fully online over Zoom meetings to become the Caregiver TLC educational free workshop in response to the needs of caregivers during the COVID-19 pandemic.  

--Dr. Jennifer Ramsey, Caregiver TLC Project Coordinator at UNC Charlotte, managed recruitment of caregivers and facilitators, implementation of the program and assessments, among other tasks. 

--Dr. Ann Choryan Bilbrey, CEO of the Optimal Aging Center, trained professionals to deliver the Caregiver TLC program, provided weekly facilitator consultation meetings, and tracked the fidelity of the program in the research protocol.

--Bruno Kajiyama, CEO of Photozig, Inc. applied the technology to deliver programs. The program website "https://caregivertlc.org" platform was developed by Photozig.

--Southminster, a non-profit Life Plan community dedicated to supporting research and healthy aging initiative, invested in the Caregiver TLC Program to enable the program to be offered free to caregivers in Charlotte and across North Carolina. As part of the team that helped recruit facilitators and educate the community about the program, Southminster promoted the research and helped make the program sustainable long term.  

Clinical Implications

Data collected from the two-year research program shows that caregivers experienced a significant reduction in depression and stress and improved how they saw their role as caregivers. "There was a positive effect no matter whether those being cared for suffered from memory loss, dementia, or chronic illness," Dr. Montoro-Rodriguez said. "In addition, even though some people believe it makes sense to develop different programs for ethnic groups and minorities, this research program indicates that the same approach serves various ethnicities equally."

Another crucial aspect of the research is that it demonstrates that a psychoeducational program such as Caregiver TLC can be effectively delivered via technology. "This is crucial because many caregivers do not have time to travel and participate in workshops in person. Those in rural areas where there are no services at all can really benefit from virtual sessions," said Dr. Montoro-Rodriguez. "Although some caregivers may be relatively inexperienced with telehealth-type service delivery at the outset, they are able to learn enough to participate in this type of program and complete on-line questionnaires.

"In addition, we also found a way to actually make the program sustainable by working with community partners to embed it into their range of services (Jewish Family Services). We also expect that other members of the community advisory board and organizations will use the free program by training their own social workers or case manager professionals to deliver it," he said. 

The Importance of Community Partners

Jewish Family Services was one of the two, diverse, non-profit partners that participated in the research phase of the Caregiver TLC program. Sheryl Gerrard, the organization's senior engagement manager, had done her certification in gerontology at UNC Charlotte when Dr. Montoro Rodriguez was the director of that program. He contacted her to be trained as a facilitator, and she was excited about the opportunity. "We had been offering a family caregiver support group, but this new psychoeducational program targeting caregivers was right in my wheelhouse," Gerrard said. "It was quite a learning experience with a pretty intense months-long process to make sure there was integrity and fidelity in the program, and that we were doing things correctly and understood objectives. I was trained as a Master Trainer, so now I can train people in our agency to facilitate groups also."

The hard work that contributed to the success of the research paid off quickly. Gerrard said she loved seeing the positive benefits in the results, and Jewish Family Services has already offered the program to new group, with plans to offer it to another group in the winter. "I think the biggest value is that it has a ripple effect. We have our own base of caregivers, and we work with many, many family members, so we can reach a whole different audience that might not have been connected through the university or Southminster. The program's themes such as stress coping and anger management are so universal across the caregiving experience. They can also be extended to support parents who have neurodiverse children, for example. The possibilities are inspiring."  

The Frankie Mae Foundation in Charlotte was also a vital part of proving the efficacy of the Caregiver TLC program. Executive Director Venitra White-Dean served as a facilitator for six to seven caregivers who were already participating in Frankie Mae's own exceptional programs. All Caregiver TLC facilitators followed the same workbook during the weekly virtual workshops to ensure all training was uniform and consistent. Keeping each group small ensured caregivers could really get to know each other, learn from each other and share advice about what might work with someone you're caring for. 

White-Dean said she learned as much as the caregivers in the training. "My mom passed away in 2020, and as I went through facilitating all the activities and practices to help caregivers cope, I wished this program had been available to help me in my own caregiving journey. I still use all the insights I learned in my daily life." 

White-Dean says the Caregiver TLC program is invaluable because it's another piece of the puzzle in a community of ongoing resources. Through its monthly meet-ups, support groups and other activities, Frankie Mae is all about giving caregivers a safe space to share their challenges and not be judged. "We have plans to integrate Caregiver TLC into our regular programs. But even if caregivers are not involved in the services of the Frankie Mae Foundation, or don't go through Caregiver TLC, it's crucial they all reach out to someone and get help to cope." 

Moving Forward

The Caregiver TLC program is now poised to benefit families far beyond its initial reach. Recognizing the diversity of caregivers across the nation, the program is currently being translated and culturally adapted for Latinos and Spanish speakers by UNC Charlotte in collaboration with other colleagues in the U.S. and Spain. "Since Latino caregivers have higher rates of dementia, we are moving forward with a goal of translating the program to serve Latino caregivers in the U.S. and other countries starting in the fall," Dr. Montoro-Rodriguez said.

"We are pleased with the outcomes of the online workshops and the opportunities for sustaining and growing the program. Our investment of charitable resources proved to be an effective way to create solutions to support caregivers, with a goal of improving not only their own well-being, but the lives of those they are caring for," said Southminster President/CEO Ben Gilchrist. 

"This is a wonderful example of how innovative partnerships can accelerate work in developing evidenced-based programs of excellence that contribute to research on aging while improving outcomes for those doing the important work of caregiving," said Tracy McGinnis, Vice President of Philanthropy & Strategic Initiatives at Southminster. 

As an evidenced-based program, Caregiver TLC now has the potential to be offered anywhere in the country, creating an even larger more supportive network of professionals and caregivers with like-minded goals of enhancing the lives of the millions who provide care to a loved one every day.

For more information, visit Caregivertlc.org 

About Southminster

A leader in the field of aging, Southminster is a non-profit, charitable Life Plan Community, providing innovative living solutions to aging across a full continuum of care. Dedicated to overall well-being, Southminster embraces living life with purpose by valuing independence and privacy, inspiring creative passions, encouraging lifelong learning, and motivating each individual's plan for wellness to its highest potential. For more information on Southminster, please visit www.southminster.org.

Contact Information:
David Jewell
The Jewell Agency
[email protected]
704-996-0165
Related Images
Dr. Julian Montoro-Rodriguez
Dr. Julian Montoro-Rodriguez

Principle Investigator\nUNC Charlotte

Dr. Dolores Gallagher-Thompson
Dr. Dolores Gallagher-Thompson

Stanford University \nDeveloped Coping with Caregiving



Original Source: Caregiver Thrive, Learn & Connect Support Program Enriches the Lives of Family Caregivers in North Carolina

The Fibroid Foundation Celebrates 10 Years of Advocacy

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The Fibroid Foundation Celebrates 10 Years of Advocacy

The Fibroid Foundation is celebrating 10 years of advocacy and hosting the 3rd Annual Fibroid Research Summit. Since 2013, the organization has been a leader in uterine fibroid advocacy — a health concern that affects 26 million women in the U.S. and millions more globally. This milestone anniversary marks a decade of erasing menstrual stigmas, designing and authoring research studies, providing access to treatment resources, and leading the way in initiating legislation on uterine fibroids and menstrual health. 

Founder Sateria Venable reflected on the past decade by saying, "I'm grateful to each community member, clinician, donor, and legislator who recognizes the importance of eliminating menstrual suffering. Menstrual health should be a concern for our community at large because it impacts each of us."

To join in the celebration, all are encouraged to visit the Fibroid Foundation's website to learn more about the 10th anniversary and the events planned. 

Fibroid Summit Program:  

Day 1 — Sept. 20, 2023, at 11 a.m. ET 

Dr. Serdar Bulun, Northwestern

William Catherino, M.D., PhD, Uniformed Services University of the Health Sciences 

Day 2 — Sept. 21, 2023, at 11 a.m. ET

Dr. Mazhar Adli, Northwestern

Shannon Whirledge, PhD, MSc, Yale

All panels will be moderated by Sateria Venable.

Register here.

Uterine fibroids are the most common gynecologic condition in women, yet research remains underfunded. Dr. James Segars, Director, Division of Reproductive Science and Women's Health Research, Professor of Gynecology and Obstetrics at Johns Hopkins University, authored a 2020 paper which concluded that, "In the subsets of bodily pain, vitality, and social functioning, fibroids were consistently a larger burden than heart disease, diabetes mellitus, and breast cancer."1 

The Fibroid Foundation continues to advocate for the passage of The Stephanie Tubbs Jones Fibroid Research and Education Act — H.R. 4572 and S.2303, introduced by Representative Yvette D. Clarke (NY-9) and Senator Cory Booker (D-NJ), respectively. Continued community support is requested by residents in each state to achieve the Congressional support required in order for both bills to be passed into law. Letters can be sent to your congressional representative via this link.

According to The Fibroid Foundation, patients are suffering in silence. Community members express concerns about limited treatment options, the high cost of treatment, insurance coverage, and difficulty finding fibroid specialists. The organization recognizes the significant health disparities that impact its community and provides support to address the disparities from a unique patient perspective. 

Fibroid Statistics: Visit the National Institutes of Health Fact Sheet on uterine fibroids to learn more

This year's Fibroid Summit Sponsors are SumitomoPharma/Pfizer and Omnia.

To partner with The Fibroid Foundation, visit https://www.fibroidfoundation.org/.

About The Fibroid Foundation

A global organization founded by fibroid patient Sateria Venable in 2013, The Fibroid Foundation has coauthored 16 medical articles, purposefully leveraging the patient experience. 

For Media Inquiries: 
Karen Janus
Phone: 844.484.7698 (IT-IS-MY-U)
[email protected] 

Tags:
#FibroidFoundation
#FibroidSummit
#FibroidBill
#SateriaVenable
#WomensHealth
#UterineFibroids
#Fibroids
#Nonprofit

Contact Information:
Sateria Venable
Founder
[email protected]
8444847698


Original Source: The Fibroid Foundation Celebrates 10 Years of Advocacy

Embark on a Journey of Creativity and Success With the Handbag Designer 101 Podcast

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Embark on a Journey of Creativity and Success With the Handbag Designer 101 Podcast
Handbag Designer 101 Launches Handbag Designer and Industry Podcast


Handbag Designer 101 Podcast

Handbag Designer 101 Podcast with handbag graphic and lineart handbags

 The countdown to a groundbreaking revelation in the world of fashion and entrepreneurship has begun. Prepare to be captivated by the launch of the highly anticipated Handbag Designer 101 Podcast, debuting on Tuesday, September 12th. Guided by Emily Blumenthal, affectionately referred to as "The Handbag Fairy Godmother," the Handbag Designer 101 Podcast promises to redefine the narrative of handbag design success.

Every Tuesday, Emily Blumenthal, Founder of The Handbag Awards and author of the handbag designer bible, "Handbag Designer 101," will introduce a stellar lineup of influential guests who have revolutionized the handbag landscape. From seasoned handbag veterans to rising stars, from social media sensations to emerging prodigies, each episode will uncover the untold stories, invaluable insights, and expert counsel that define the handbag universe. To inaugurate the series, the Handbag Designer 101 Podcast proudly presents a trio of handbag luminaries:

  • Monica Botkier: The revered handbag designer veteran celebrated for her iconic creations.
  • Tanner Leatherstein: The creative mind behind Instagram-famous handbag designs that have taken the digital world by storm.
  • Antoine Manning of Homage Year: A fresh, innovative newcomer bringing a contemporary perspective to the industry.

In addition to these prominent figures, the podcast features an eclectic assembly of independent designers from across the globe, industry experts, trend analysts, and retail pioneers, including South African luxury designer, Adrian Furstenburg, Co-Founder of FABSCRAP, Camille Tagle, and social media sensation, "Afropuff Jada" Holmes who can make 'anything' into a handbag, collectively weaving a comprehensive narrative that embodies the multifaceted journey of establishing a triumphant handbag brand.

"The Handbag Designer 101 Podcast is a testament to the untold stories and immeasurable wisdom that fuel the heart of the handbag industry," says Emily Blumenthal. "Whether you're a seasoned designer or a burgeoning creative, this podcast empowers you with the knowledge and inspiration to manifest your handbag dreams." Emily's advocacy has propelled independent handbag designers into illustrious realms such as Bloomingdale's, Macy's, and Saks Fifth Avenue.

The Handbag Designer 101 Podcast is set to make its mark on Tuesday, September 12th, available for streaming on all major podcast platforms. Fashion enthusiasts, creative minds, and industry insiders are invited to embark on this illuminating journey into the essence of handbag design.

For press inquiries, interviews, or further information, please contact: [email protected] 

Follow Handbag Designer 101 Podcast on:

Listen to "Handbag Designer 101" on Apple Podcasts, Spotify, or your preferred podcast platform.

Note to Editors: High-resolution images and additional background information about Emily Blumenthal and the Handbag Designer 101 Podcast are available upon request.

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Contact Information:
Emily Blumenthal
Founder
[email protected]
646-209-1418


Original Source: Embark on a Journey of Creativity and Success With the Handbag Designer 101 Podcast

ISSA Announces New International Distributor Partnership With ModuVated Fitness

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ISSA Announces New International Distributor Partnership With ModuVated Fitness
Bringing ISSA's Spanish-Translated Certified Personal Trainer Education to Mexico to Empower Aspiring Fitness Professionals to Enter the Industry


MODUVATED FITNESS AND ISSA

MODUVATED FITNESS AND ISSA

The International Sports Sciences Association (ISSA), the global leader in online fitness and wellness education, has teamed up with Mexico's premier health and wellness brand ModuVated Fitness to educate and up-skill aspiring fitness professionals in Mexico. 

This month, ISSA Education Professionals will travel to ModuVated's state-of-the-art facilities in Cabo San Lucas and provide their bilingual instructors with intense in-person training and the tools necessary to teach ISSA CPT courses live as a supplement to the ISSA online course and exam.

This new program effectively opens opportunities for aspiring fitness professionals to follow their dreams and enter the fitness and wellness industry. 

"This collaboration is a wonderful opportunity for ISSA to distribute our new Spanish-translated CPT in Mexico via ModuVated's highly esteemed trainers and reach more individuals looking to establish careers in fitness," said Kurt Magnum, Director of Partnerships for ISSA.

For the past 14 years, Senegal native Modu Seye has developed ModuVated Fitness with a vision to provide healthy, happy, and confident lifestyles for all. Seye says, "We are thrilled to partner with the global leader in fitness education, ISSA. Together, we're raising the bar in Mexico ensuring that top-notch, well-trained professionals help our community reach their goals." 

"At ISSA, our mission is to empower people to improve lives through fitness, wellness, and nutrition and this partnership helps us to reach more individuals to do just that," said ISSA CEO Andrew Wyant. 

Find out more about ISSA's Spanish-translated personal training course here.

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About ISSA:

The International Sports Sciences Association (ISSA) is the global leader in online fitness and wellness certifications. For over 30 years, ISSA has been committed to delivering comprehensive, cognitive, and practical education that's grounded in industry research. Rooted in Certified Personal Training certifications, ISSA offers over 50 fitness and wellness certifications and specializations, including a Yoga Alliance-recognized Yoga 200-Hour Teacher Training Course, Certified Personal Training en Español, Health Coaching, Nutrition, and more. ISSA has educated nearly half a million trainers across 176 countries while driving toward their vision to connect 100 million people to the power of healthy living by 2030.

Contact Information:
Kim Kisner
PR Lead
[email protected]
313-333-2163

Colleen Reddington
Marketing Manager
[email protected]
800-545-8111


Original Source: ISSA Announces New International Distributor Partnership With ModuVated Fitness

30 Years of Groundbreaking Medical Education Features Award-Winning Speakers

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30 Years of Groundbreaking Medical Education Features Award-Winning Speakers
CEO and Founder of Neurovations Dr. Eric Grigsby Celebrates Three Decades of Innovation in Chronic Pain Management at 30th Napa Pain Conference

The 30th Napa Pain Conference concluded on Aug. 20, 2023, celebrating three decades of unwavering commitment to advancing treatments and research for pain and neurological disease. The conference brought together global experts, researchers, clinicians, and healthcare professionals who shared groundbreaking insights in the field of pain medicine.

Nobel Prize recipient Dr. Carolyn Bertozzi delivered the 2023 Lindahl Lecture. Renowned for her groundbreaking research in the field of chemical biology, coining the term and field of bioorthogonal chemistry, Professor Bertozzi has been the recipient of honors of the highest scientific order, including a MacArthur Fellowship and the Breakthrough Prize in Life Sciences, as well as the 2022 Nobel Prize in Chemistry.

"Dr. Bertozzi's keynote session on her work with cancer cells was quite simply one of the best sessions I have ever attended. She has a unique and brilliant mind, and a gift for collaboration and mentorship," said Dr. Eric Grigsby, founder and CEO of Neurovations, a patient care and innovation company. 

The Lindahl Lecture is named for Dr. Grigsby's early mentor Dr. Sten Lindahl, former Chair of the Nobel Committee. Past Lindahl Lectures include Bruce Beutler, MD, 2011 Nobel Prize recipient in Medicine, and Jennifer Doudna, PhD, Nobel Prize recipient in 2020 and developer of CRISPR technology.

The conference also honored Dr. Lawrence Poree with the inaugural Dr. Elliot Krames Award for Excellence in Translational Neuromodulation and Dr. Peter Staats, Chief Medical Officer, National Spine and Pain Centers, who presented the Legacy Lecture for dedication to the field of chronic pain. 

"I am truly honored to have been chosen to deliver the Legacy Lecture at the 30th Napa Pain Conference. It's a testament to the dedication and collaborative spirit of all those who have contributed to this journey. I am reminded of the challenges we've overcome and the breakthroughs that have transformed patient care. This legacy fuels our determination to continue pushing the boundaries of pain research and treatment, ensuring a brighter and pain-free future for all," Dr. Staats said.  

The annual vineyard dinner was held at the Grigsby Vineyard in Yountville, marking the occasion for the inaugural release of the Grigsby Vineyard Cabernet Sauvignon and Petit Syrah. 

"The Grigsby family's legacy dates to 1846 when our forebear John Grigsby first cultivated this land. Today, we honor his pioneering spirit with organic farming and a goal to produce the finest wine the land will give us. I can't think of a better way to launch Grigsby Vineyard than to share it with this incredible group," Dr. Grigsby said.

Experts in the field of interventional pain medicine presented Dr. Grigsby with an award recognizing his dedication to innovation in the field of chronic pain management. The award, which featured a video of well-wishers from across the globe, was presented by Dr. Grigsby's own daughter Giovanna Grigsby, currently enrolled in medical school at Mayo Clinic. 

"I was overwhelmed by the kindness from those I respect so much. To hear doctors Carol Warfield, Daniel Carr and Elliott Krames — just to name a few — say such kind things about the past 30 years of work, was humbling. The success of the conference underscores its significance as a pivotal platform for advancing pain management knowledge and practices. As the field continues to evolve, the Napa Pain Conference remains committed to driving innovation, fostering interdisciplinary cooperation, and improving the lives of those living with pain." 

Contact Information:
Krista Clark
Marketing Director
[email protected]
7072529665




Original Source: 30 Years of Groundbreaking Medical Education Features Award-Winning Speakers

New Online Nutrition Program Marks a Pivotal Advancement for Type 2 Diabetes Management With Outstanding Clinical Outcomes

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New Online Nutrition Program Marks a Pivotal Advancement for Type 2 Diabetes Management With Outstanding Clinical Outcomes

T2Diet Program Participant \u2014 Dean

New Scientifically Supported Online Nutrition Program Changing Type 2 Diabetes Health

Innovative digital health research published in NATURE Nutrition & Diabetes on Aug. 27, 2023, demonstrated the effectiveness of the T2Diet Program to change the health of people living with type 2 diabetes. Led by Dr. Jedha Dening, type 2 diabetes nutritionist and founder of Diabetes Meal Plans, the T2Diet Study has shown that people can achieve significant improvements in blood sugar control, and reductions in weight and diabetes medications, in just a short time. 

"The findings of the T2Diet Study are incredibly important and exciting," remarks Dr. Dening. "The study proves we can make a significant and positive impact on people's lives by reaching them anywhere to provide effective, accessible and practical solutions."

Addressing a Critical Gap in Diabetes Management

With type 2 diabetes impacting an estimated 34 million Americans and projected to affect 1.3 billion globally by 2050, innovative solutions are paramount. 

"With the growing number of people living with type 2 diabetes, scientifically proven digital interventions are the best way to reach people with the education and support they urgently need," said Dr. Dening. 

Life-Changing Results of the T2Diet Study

In the 16-week blinded randomized controlled trial, 98 participants were divided into two groups: one engaging with the online T2Diet Program plus standard care, and the other continuing standard care alone.

T2Diet Program participants saw vastly improved blood sugar control with an average reduction of nearly 1% in hemoglobin A1c, an average weight loss of 9.6 pounds and considerably reduced diabetes medications. In contrast, the standard care group saw marginal health changes and increased medication.

"Beyond the confines of the study, we've seen people all across America, Canada and Australia achieving great results with the program," notes Dr. Dening. "One person recently lowered their A1c by 4% and shed 40 pounds in 16 weeks. Witnessing these life-changing results is truly inspiring." 

A Leap Forward for Diabetes Health

"Research on the effectiveness of digital dietary interventions for people with type 2 diabetes is still extremely limited, so this is a big step forward," said Dr. Dening. 

The success of the T2Diet Program marks a pivotal advancement in the field of type 2 diabetes management. By harnessing the power of online nutrition education and support, people can access the tools and resources they need to achieve lasting health improvements.

The T2Diet Program is available to people around the globe, and provided alongside standard care, the study results show the enormous potential to make a real difference in many people's lives.

For more information on the T2Diet Program, visit https://t2diet.com 

Contact Information:
Paul Quinton
Manager
[email protected]


Original Source: New Online Nutrition Program Marks a Pivotal Advancement for Type 2 Diabetes Management With Outstanding Clinical Outcomes

The Movie Critic: Rumors say Quentin Tarantino offered the lead to Paul Walter Hauser prior to the strikes

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The Movie Critic: Rumors say Quentin Tarantino offered the lead to Paul Walter Hauser prior to the strikes

Character actor Paul Walter Hauser is said to have been given the opportunity to star Tarantino’s last film until the strikes delayed filming.

All eyes are on the development of the tenth film from Quentin Tarantino. The prolific director has declared that his last film will be a feature titled The Movie Critic. After a strong debut with Reservoir Dogs, Tarantino cemented his place in pop culture and with film nerds everywhere with his sophomore film Pulp Fiction. Since the success of that film, the director has become a household name, and people continued to gravitate toward the filmmaker’s throwback style amid the graphic violence, language and foot fetish.

Casting for a Tarantino film is usually as anticipated as the plot details. The Kill Bill director has a penchant for working with legacy actors as well as some obscure names. Industry insider Daniel Richtman has revealed that Tarantino is rumored to have offered the starring role in his final film to character actor Paul Walter Hauser. Hauser can be seen for his scene-stealing roles in projects like I, Tonya and Cobra Kai. He has also been able to show off his acting chops in a Clint Eastwood film that he also headlined, Richard Jewell.

The Screen Actors Guild strike has currently put a hold on any deal or formal announcements, but the role that Hauser would likely be playing is the title role of the movie critic — Jim Sheldon. Tarantino himself would write with Sheldon as a pseudonym for the New Beverly Cinema website. New Beverly is the throwback movie theater that Tarantino currently owns.

The plot for The Movie Critic is currently under wraps, although it is said that it will not involve the concept of revenge despite Tarantino describing the Jim Sheldon character as “Travis Bickle is he was a movie critic.” All that is currently known is the film takes place in 1977, which puts it in the year of the release of Star Wars. Perhaps it’s foolish to expect any kind of heavy reference since Tarantino squabbled over Disney taking over screens when both The Force Awakens and The Hateful Eight were set to open around the same time. The film was supposed to start production this fall, but as the strikes march on, no new word has been revealed on when the movie has rescheduled it’s principal photography.

Originally published at https://www.joblo.com/the-movie-critic-quentin-tarantino-paul-walter-hauser/

WTF Happened to Chris O’Donnell?

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WTF Happened to Chris O’Donnell?

In this episode of WTF Happened to this Celebrity, we look back on the life, career, and achievements of gifted actor Chris O’Donnell.

In the 90s, Chris O’Donnell was one of Hollywood’s most prominent young heartthrobs. Whether it was acting opposite Al Pacino in Scent of a Woman or playing a young D’Artagnan in the Disney version of The Three Musketeers, it can’t be denied that the movie that put his career into overdrive was Batman Forever. In it, O’Donnell reinvented the role of Batman’s ward and sidekick, Robin, for the nineties, with him an acrobatic badass that proved so popular that the next movie was Batman and Robin. And there is where things started to change, with Joel Schumacher’s sequel ridiculed. 

Even still, O’Donnell made a few good movies after, including the underrated rom-com The Bachelor and the terrific Martin Campbell action movie Vertical Limit. However, his career never regained the momentum it had in the nineties. Yet, despite everything, he later went onto a long run on NCIS: Los Angeles, so while his feature film career cratered, his career on the small screen flourished. Thankfully, there’s plenty of O’Donnell to go around, thanks to NCIS: Los Angeles, with the actor being an integral part of the show from 2009 to 2023. While O’Donnell’s NCIS character, G. Callen, neglects the actor’s elaborate sock-nunchuck skills, the role keeps O’Donnell in the mix of one of the most beloved procedurals on television.

What’s your favorite role of O’Donnell’s? Did you enjoy his run on Head Cases or his part as Dr. Finn Dandridge in the long-running medical drama Grey’s Anatomy? Do you think O’Donnell will return to the silver screen after conquering the television space? Is he the superior Robin? Let us know in the comments. 

In this episode of WTF Happened to this Celebrity, we look at his career ups and downs and appreciate one of the more underrated actors of his era.

Originally published at https://www.joblo.com/wtf-happened-to-chris-odonnell/

Halloween: Resurrection (2002) – WTF Happened to This Horror Movie?

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Halloween: Resurrection (2002) – WTF Happened to This Horror Movie?

The Halloween: Resurrection episode of WTF Happened to This Horror Movie? was Written by Eric Walkuski, Edited and Narrated by Tyler Nichols, Produced by Andrew Hatfield and John Fallon, and Executive Produced by Berge Garabedian.

You knew we’d have to tackle this one eventually, so let’s just hold hands and get through it together.

Halloween: Resurrection (watch it HERE). The two words combined are enough to send chills down the spines of even the most hardcore movie fans. It causes trick-r-treaters to cross to the other side of the street; it’s the movie your parents warned you about. It’s the movie where this happens. To watch it is to wonder how, as in, How did we get here? From the terrifyingly simple 1978 classic to this silly, slapdash goof. It has its defenders, I think, but most of us agree that it lives near the bottom of the barrel of the Halloween franchise – and maybe the horror genre itself. But we’re completists, and truth be told the hows and whys of Resurrection’s existence are much more interesting than the movie itself, so thanks in advance for logging into our chat room so we can all figure out WTF Happened to Halloween: Resurrection.

1998’s Halloween H20 was by and large a decent success for Dimension Films, not to mention a fitting conclusion to the saga of Laurie Strode and her evil brother Michael Myers. With a pretty definitive conclusion that saw the beheading of the masked antagonist, it looked as though we got that rare thing in the horror world: a satisfying conclusion to a franchise. But if we’re being honest, no one was naive enough to believe it would be the very end of The Shape, and thanks to the above-average box office haul for the modestly-budgeted film, a return from the grave was quickly brewing for Mr. Myers. Longtime producer Moustapha Akkad was never truly going to kill off his cash cow, and had even made sure they shot a scene during H20’s production that indicated Michael hadn’t actually died at the conclusion.

For her part, Jamie Lee Curtis was dismayed to learn another film was in the works and wanted no part of it, but eventually agreed to appear in it if she got killed off quickly in the first act. The producers’ initial idea was to have Laurie Strode commit suicide at the beginning of the film, but Curtis vetoed the idea immediately. In fact, it was allegedly her idea that the movie would open with Laurie in an asylum, and though the early scripts called for no more than a 30 second cameo from Curtis, she ended up shooting for four days on the picture before getting her death wish for Laurie.

But we’re getting a bit ahead of ourselves. After H20, Moustapha Akkad and his producer Paul Freeman were looking for ways to keep the franchise going. Intriguingly, the guys at Dimension Films pitched the idea of a Halloween movie that didn’t feature Michael Myers at all, ala Season of the Witch. Unsurprisingly, Akkad rejected that concept, as the notion of making Halloween an anthology series had long ago been seen as a mistake. H20 scribe Robert Zappia supposedly came up with a pitch that was rejected, while Halloween 6 writer Daniel Farrands had pitched an idea subtitled Lord of the Dead that would actually see Laurie revealed as the killer at the end. No dice on that one either.

The producers toyed with the idea of bringing back Josh Hartnett’s John Tate at one point, while also looking to bring back LL Cool J’s surviving security guard character, but neither panned out. There was evidently some talk of bringing back Halloween 4 and 5 star Danielle Harris, but obviously that never came to fruition either. Enter director-screenwriter Larry Brand, who shared an agent with producer Paul Freeman. Brand had impressed Akkad with a spec script of his, prompting the Halloween godfather to ask him for any potential ideas he might have in regards to resurrecting Michael Myers. Brand divulged a concept he’d come up with years earlier involving a killer stalking people in a house that has been rigged with cameras – sort of The Real World with a murderer. Akkad responded positively to the concept and subsequently pitched it to Dimension. Soon enough, Brand received the greenlight to write the film, which would now take place not in some random hideaway but the legendary Myers house. This new Halloween would go on to have several titles, such as Halloween: The Homecoming, H2K: Evil Never Dies, and believe it or not, Halloween: MichaelMyers.com. You have to love the early 2000s.

In any event, because the producers wanted to make it clear Myers was returning, ultimately the subtitle Resurrection was landed upon. It would open with the revelation that Myers had put his mask on a hapless paramedic at the last minute, an idea hatched by H20’s co-writer Kevin Williamson during the production of that film. After Michael successfully finds Laurie and dispatches her, he’s off to Haddonfield yet again to return home, only to find it’s now the scene of a reality show where contestants roam the hallways of his onetime abode. Of course, he has no choice but to dispatch the obnoxious participants of said reality show, making this the first time in the franchise the audience and Michael Myers are on the same page.

To direct the film, the producers went to TV director Whitney Ransick, who turned it down, as well as Halloween 4 helmer Dwight Little, who also rejected the offer. Ultimately, the decision was made to bring aboard Rick Rosenthal, who directed Halloween II some twenty years earlier. Incidentally, Rosenthal’s Halloween ties go deeper than that: he’s also the husband of actress Nancy Stephens, who portrayed Nurse Marion Chambers in Halloween, Halloween II, and Halloween H20, in which her character was finally killed off. Rosenthal hadn’t directed much horror since Part II – if you don’t count The Birds II that is – but he’d done plenty of television work throughout the years and could jump back into the series with ease. He would also insert himself into the proceedings with a cameo as a professor toward the beginning of the film.

Production commenced in May 2001 in Vancouver, where a convincing replica of the Myers house was built on a soundstage, with appropriate aging and distress over twenty years. Of course, when you watch the movie it seems like the interior of it belongs to a house about three times bigger than the exterior would suggest, but that’s a different story.

Who would be playing the victims of the Shape? As mentioned, the studio wanted to bring back LL Cool J since the general audience responded so well to him, but the rapper-turned-actor was too busy, or maybe just ready to move on. Sensing that the same quote-unquote urban audience that helped make H20 a hit would respond to another hip hop star in a leading role, the producers set about finding their next unconventional star. “Gangsta’s Paradise” singer Coolio was brought in to audition for the film, but ultimately, they settled on New York’s own Busta Rhymes, at the time one of hip hop’s most prolific entertainers. Helpfully, Busta also had some acting experience, having appeared in John Singleton’s Higher Learning and Shaft… Rhymes would end up improvising a great deal of his dialogue on set, bringing what you have to admit is an infectious energy to the character of Freddy.

The final girl character, Sara, was to be played by Australian actress Jacinda Barrett, who’d had a supporting role in Urban Legends: Final Cut. But before filming began, Barrett dropped out to join a television show, so the role went to Bianca Kajlich, who had already been cast as Sara’s perky best friend, Jen Danzig. After Kajlich pivoted to the lead role, actress Katee Sackhoff, who’d been cast as sultry Donna, was moved over to the Jen Danzig part. An interesting tidbit about Ms. Kajlich: she apparently cannot scream which is a fascinating phenomenon in its own right, but especially troublesome for the lead in a horror movie. Hence, all her screams had to be added in during post-production.

Playing Michael Myers this time was professional stuntman Brad Loree, taking over for Chris Durand who portrayed the Shape in H20. Loree was called by one of the people at Dimension asking if he’d be willing to try out for Michael Myers’ stunt double. Not being a big horror fan, Loree initially thought they meant the comedian Mike Myers, which he thought was rather odd. When it became obvious that it was the masked maniac, Loree auditioned for Rick Rosenthal and the film’s producers simply by walking in a straight line, mimicking the Shape’s infamous gait. Before he knew it, Loree was told he wasn’t just going to be a stunt guy but Michael Myers himself, and he’d have to go to L.A. to get a head-cast done for the mask.

Production in Vancouver lasted approximately five weeks, with another week of reshoots eventually added on. As is often the case, it was apparently not easy working with the Weinstein brothers on the show, as they’d constantly demand rewrites and reshoots on the film. A new ending was thought up seemingly every other day, and the production ended up shooting four different finales. Trying to make the best of it, Rosenthal thought they should release all four versions of the film theatrically, with the audience unaware which ending they’d be getting, but that idea was obviously not very practical.

One notable deleted scene involved the death of Tyra Banks’ character, Nora, who is Freddie’s right-hand woman. Nora’s death by strangulation was filmed but later cut from the final product because it was thought there should be a scene where a character you didn’t realize was dead is discovered by the hero. Still, publicity shots released before the movie clearly show Michael Myers ready to pounce Nora from behind.

Editing the film was a challenge in general. All of the cameras the actors are seen wearing were actually recording, and the post-production team found themselves with some 20-plus hours of video footage. Editing that and making it coalesce with the objective 35mm footage proved to be difficult. A 40-minute cut of exclusively webcam footage titled Halloween: Resurrection – WebCam Special can be viewed on the Blu-ray or on YouTube… And… honestly? As its own mini-found footage horror flick, it’s not bad. It certainly beats Resurrection in terms of effectiveness.

The film was originally meant to be released in September of 2001, but delays pushed that date back to April 2002. Thanks to reshoots, it was pushed back further, this time to July 12th, marking the first and only time a Halloween film would be released in July. The posters for the film prominently display a short-haired Jamie Lee Curtis, looking exactly like she did in H20 but a far cry from her appearance in Resurrection.

It was a busy weekend at the movies, with the second weekend of Men in Black II, and the openings of Road to Perdition and Reign of Fire all competing with Resurrection for filmgoers’ attention – and money. The movie got off to an adequate start, making $12 million opening weekend in just under 2,000 theaters, but the next weekend saw it drop over 55%, then another $51% the following weekend. All in all, it made $30 million at the domestic box office, a less impressive number than H20’s $52 million. Its budget was reportedly around $15 million, so the film likely eeked out a profit thanks to home video, but the damage to the good Myers name had been done in with one swift kick from Busta Rhymes.

Of course, there would be no sequel to Resurrection, it being the official end to that particular timeline in the Halloween franchise. Five years later, Michael would get a drastically different look thanks to Rob Zombie and his Halloween reboot, but that’s a topic for a different show.

In recent years, both Jamie Lee Curtis and John Carpenter have expressed, let’s say, distaste for how Resurrection turned out, with Curtis referring to it as a “joke.” For his part, Carpenter had this eloquent reaction to it, quote, “Oh my god. Oh lord, god. What the hell? I couldn’t believe it.” End quote… He speaks for plenty of us.

If nothing else, Halloween: Resurrection always gives us horror fans plenty to laugh about whenever spooky season comes around. Indeed, in its own way, it’s an unforgettable entry in the genre, so it will always have that going for it. And that’s about as much as we can say for it.

Also: Happy Halloween, motherf-ckers!

A couple of the previous episodes of WTF Happened to This Horror Movie? can be seen below. To see more, head over to our JoBlo Horror Originals YouTube channel – and subscribe while you’re there!

Originally published at https://www.joblo.com/halloween-resurrection-wtf/