Sleepaway Camp’s 40th anniversary celebrated with a “making of” book and soundtrack EP
Originally published at https://www.joblo.com/sleepaway-camp-book/
MENLO PARK, Calif., August 11, 2023 (Newswire.com) - BillionToOne, experts in fetal DNA quantification, announced today that Scientific Reports published a study1 of the UNITY Fetal Antigen Noninvasive Prenatal Test (NIPT). The validation study marks an inflection point for patients who are at risk of Hemolytic Disease of the Fetus and Newborn (HDFN) due to the assay's unmatched accuracy coupled with its novel approach.
In this validation study co-authored by scientists at BillionToOne and Brigham and Women's Hospital and senior-authored by Dr. Kathryn Gray, MD, PhD, the UNITY Fetal Antigen NIPT correctly determined the antigen status for 1,061 preclinical samples resulting in 100% sensitivity and specificity and achieved 99.9% precision on 1,683 clinical samples. Clinical samples with known outcomes (neonatal antigen genotype/serology) were also evaluated with 100% concordance across 93 antigen evaluations in 30 alloimmunized pregnancies. Impressively, 100% accuracy was achieved while maintaining a low no-call rate of 0.1%.
HDFN is a serious condition that occurs when a pregnant patient's antibodies cross the placenta and attack the fetal red blood cells. When most severe, HDFN can cause life-threatening anemia in the fetus. Prior to the availability of UNITY Fetal Antigen NIPT, identifying patients at highest risk of HDFN was error-prone and cumbersome, necessitating a partner's sample and invasive diagnostic testing.
This new approach with UNITY Fetal Antigen NIPT is set to revolutionize identification and management for patients at risk of severe HDFN due to the assay's greater accuracy and convenience compared to existing tests like amniocentesis, which comes with many risks, particularly for patients at risk of HDFN.
The publication also highlights how UNITY Fetal Antigen NIPT can also be used to nearly eliminate unnecessary prophylactic treatment for 40% of RhD-negative pregnancies. The assay's unique capability to accurately assess non-deletion RHD gene variants, which are more prevalent in non-European populations, underscores the test's applicability and validity across ethnically diverse populations. This capability reduces the assay no-call rate to 0.1%, significantly lower than any previous RhD assays and addresses any potential concerns against front-line RhD NIPT screening.
"At BillionToOne, we are uniquely positioned to do the unthinkable with genetic testing due to our QCT technology," said Oguzhan Atay, PhD, CEO of BillionToOne. "The published validation data for UNITY Fetal Antigen NIPT is a perfect example of this, ultimately setting a new standard for patients and providers in the management of HDFN." As stated in the publication, "the clinical implementation of NIPT can significantly improve the standard of care for both prevention of RhD alloimmunization and management of alloimmunization in pregnancy."
About the UNITY Fetal Antigen NIPT
The UNITY Fetal Antigen Test Screen was first launched in September 2022 for pregnant patients alloimmunized against RhD, C, c, E, K (Kell), and Fya (Duffy) red blood cell (RBC) antigens, and can be performed as early as 10 weeks of gestation. Using BillionToOne's proprietary molecular counting technology or Quantitative Counting TemplatesTM (QCTs), this NGS-based assay detects the presence or absence of the genetic variants that code for corresponding fetal antigens to accurately identify which patients are truly at highest risk for developing HDFN. Since its launch, over 1,000 UNITY Fetal Antigen NIPT have been ordered for clinical use. About 60% of those patients received a "Not Detected" Fetal Antigen result, sparing the expecting parents from unnecessary follow-ups and undue anxiety.
About UNITY Fetal RhD NIPT
The UNITY RhD NIPT was launched in 2020 for pregnant patients with RhD-negative blood type at the gestational age of 10 weeks or higher. Up to 40% of RhD-negative pregnant individuals carry an RhD-negative fetus and do not need the administration of Rho(D) immune globulin. The QCT technology-based quantitative approach with NGS enables the assay to detect fetal RhD status both for the common RHD gene deletion and other RHD variants such as RHDΨ, significantly reducing the no-call rate while maintaining 100% sensitivity and specificity.
About BillionToOne
Headquartered in Menlo Park, California, BillionToOne is a precision diagnostics company on a mission to make molecular diagnostics more accurate, efficient, and accessible for everyone. The company's patented QCT™ molecular counter platform is the only multiplex technology that can accurately count DNA molecules at the single-molecule level.
For more information, please visit www.billiontoone.com.
For more information about the trial or the collaboration, please contact [email protected].
1 Alford, B., Landry, B.P., Hou, S. et al. Validation of a non-invasive prenatal test for fetal RhD, C, c, E, K and Fya antigens. Sci Rep 13, 12786 (2023). https://doi.org/10.1038/s41598-023-39283-3
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BONITA SPRINGS, Fla., August 11, 2023 (Newswire.com) - Discovery Senior Living ("Discovery") is excited to introduce its latest regional management company, LakeHouse Senior Living ("LakeHouse"). The creation of the company further diversifies Discovery's growing, multi-brand portfolio and establishes a stronghold in the Midwest surrounding the Great Lakes. It also marks another milestone in Discovery's growing regional management company structure, aimed at providing exceptional senior living experiences to a local audience. LakeHouse Senior Living will focus on operating communities in northern Indiana, Illinois, Michigan, Ohio, western Pennsylvania and Wisconsin, catering to the unique preferences and needs of seniors in this region.
Discovery executed the launch of LakeHouse Senior Living with the commencement of management of numerous new communities, as well as the assimilation of an existing portfolio of communities currently being operated by Discovery in the region.
As one of the operating company subsidiaries of Discovery Senior Living, LakeHouse will operate as a local management company with a full management team and will benefit from the robust support services provided by the Discovery Operational Support Center located at the company's Florida headquarters.
Further bolstering its executive leadership team, Brad Poterack has been appointed Chief Operating Officer of the new LakeHouse management company. Poterack brings to the Discovery enterprise more than 25 years of experience as a solution-minded leader with proven success across two dynamic industries. He previously worked in a senior management role at Macy's and most recently served as Senior Vice President, Operations for Enlivant, assisted living communities, a post he occupied since 2019.
"We are excited to introduce LakeHouse Senior Living as our newest regional management company and brand," said Richard J. Hutchinson, CEO of Discovery Senior Living. "This addition represents the continuation in our multi-year strategic efforts to marry the best of customized local community management with the support of a robust and sophisticated business process curated at the parent company level. We are also very excited to have Brad join our executive team and look forward to working with him to learn from his experience, both within and outside of the seniors housing industry, to create tailored senior living solutions for our valued customers."
About Discovery Senior Living
Discovery Senior Living is a family of companies that includes Discovery Management Group, Morada Senior Living, TerraBella Senior Living, LakeHouse Senior Living, Integral Senior Living, Discovery Development Group, Discovery Design Concepts, Discovery Marketing Group, and Discovery At Home. With three decades of experience, the award-winning management team has been developing, building, marketing, and managing diverse senior-living communities across the United States. By leveraging its innovative "Experiential Living" philosophy across a growing portfolio of nearly 300 communities and approximately 30,000 homes in nearly 40 states, Discovery Senior Living is a recognized industry leader for innovation and lifestyle customization and, today, ranks among the five largest U.S. senior living operators.
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TEL AVIV, Israel, August 11, 2023 (Newswire.com) - Imagene, an emerging leader in AI-based precision oncology, is proud to announce the launch of the ImageneOI platform on Oracle Cloud Infrastructure (OCI). The innovative platform, supported by proven clinical benefits, sets a new paradigm in cancer diagnostics by enabling rapid AI-based molecular profiling from biopsy images alone, overcoming key barriers and limitations in current diagnostic processes. ImageneOI already proved its significant impact under research on treatment initiation and averting radiation for two cancer patients, as published in a recent case report in the Journal of Clinical Pathology.
"We're confident in selecting Oracle as our cloud provider and are pleased to join forces with Oracle in our mission to make advanced technologies drive better patient care," said Dean Bitan, co-founder and CEO of Imagene. "Oracle is not only delivering consistent, high-performance computing with widespread global reach, but its focus on the healthcare sector has played a crucial role in enabling us to bring this transformative service to the forefront of cancer diagnostics."
For AI inference computation and to process data at scale, Imagene partnered with Oracle to run its ImageneOI platform on OCI and will take advantage of OCI Supercluster and OCI AI infrastructure technology. OCI's cost-effective, high-performance computing enables the ImageneOI platform to offer rapid biomarker profiling and to deliver impressive performance of approximately two minutes from uploading a digitized biopsy image to receiving a biomarkers status report.
"Saving lives is technology's single most important use," said Safra Catz, CEO of Oracle. "We are proud that Oracle's highly performant and secure cloud infrastructure will help Imagene improve access to care, drive informed decisions, lower costs, and ultimately save lives."
ImageneOI aligns with oncology clinical guidelines that emphasize the importance of obtaining molecular testing for actionable cancer biomarkers before initiating treatment. This breakthrough technology paves the way for improved and personalized cancer care. It facilitates informed decision-making for optimal treatment strategies by reducing turnaround times from weeks to minutes.
The platform transforms cancer diagnosis by addressing a significant gap in the current healthcare landscape. In the United States, approximately 80 percent of cancer patients choose to receive treatment in community settings. In addition, 64 percent of lung cancer patients, which is the deadliest cancer, do not receive the optimal treatment mostly due to biomarker testing-related challenges and limited access to comprehensive Next-Generation Sequencing (NGS). Up to 30 percent of tested patients do not receive guidelines-recommended biomarkers testing results prior to first-line therapy initiation. This accessibility issue and under-tested populations presents a major obstacle to effective cancer treatment.
The pressing need and demand for rapid and accurate cancer diagnosis pose a significant challenge in advancing precision oncology. This challenge is highlighted by the projected rise in cancer incidence, lengthy turnaround times, and issues with tissue inadequacy. The accessibility of the ImageneOI platform on OCI makes it an invaluable rapid molecular profiling resource for research institutions and medical centers globally.
In conjunction with the launch, Imagene is initiating an Early Access Research Program. Interested parties are encouraged to get in touch for more information at [email protected].
About Oracle:
Oracle offers integrated suites of applications plus secure, autonomous infrastructure in the Oracle Cloud. For more information about Oracle (NYSE: ORCL), please visit us at www.oracle.com.
About Imagene:
Imagene is an emerging leader in AI-based precision oncology. The company leverages AI to profile, within minutes, a broad range of cancer biomarkers from a digitized biopsy image alone, providing physicians with immediate oncology intelligence to ensure optimal treatment for all cancer patients. Visit imagene-ai.com
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The horror movie My Animal, starring Amandla Stenberg and Bobbi Salvör Menuez, has secured an R rating ahead of its September release
The horror romance My Animal – which stars Amandla Stenberg of Bodies Bodies Bodies (read our review of that one HERE) and Bobbi Salvör Menuez of Nocturnal Animals (which we reviewed at THIS LINK) – will be receiving a limited theatrical release on September 8th, with a digital release following on September 15th. With those dates right around the corner, the ratings board at the Motion Picture Association has gone ahead given the film an R rating for “language throughout, sexual content, nudity, some drug use and violence“.
My Animal is coming our way from Paramount Global Content Distribution. The feature directorial debut of Jacqueline Castel, who was working from a screenplay by first-time feature writer Jae Matthews, the film is set in a small northern town and tells the story of Heather, an outcast teenage hockey goalie (Menuez), who falls for the town’s newcomer (Stenberg), an alluring but tormented figure skater. As their relationship deepens, Heather’s growing desires clash with her darkest secret, forcing her to control the animal within.
And yes, those who have had the chance to watch My Animal already have confirmed that this is a werewolf story. So has director Castel, who provided the following statement: “My Animal is a story about inheritance: of what gets passed through our lineage and how that defines us as individuals. It is also a story about first love and how that can serve as a catalyst for radical change, revealing what we most need and what most needs healing within us.
Like Heather, I understand the quiet despair and isolation of being an outsider in a small town, and of rebelling against it in youth only to discover that the most treasured and distinctive aspects of my selfhood derive from the very things I attempted to reject. What made me different also defined and ultimately transformed me.
In Jae Matthew’s screenwriting, I found the pain and joy of our mirrored adolescent struggles, our complex family relations, and the difficulty of navigating our earliest and most formative relationships. The real battle we each waged in youth, and the one Heather’s character must also face, is finding the courage of self-acceptance and self-expression. Through the struggles of these characters we encounter what works and what does not in the quest for identity, authenticity, and self-actualization, and the courage we must summon in the face of personal crisis and discrimination. This classical, outsider framework translates beautifully to the mythology of the werewolf.
In My Animal, I invite the viewer to get lost in the otherness of Heather Anderson. In so doing, I not only compel the audience to feel connected to a character who at first may appear to have little in common with them, but also to learn the same lessons that she does: only by embracing the traits that make us outcasts, and even subject to scorn, do we learn to become fully ourselves.“
My Animal was produced by Andrew Bronfman and Michael Solomon, with Stenberg and Menuez serving as executive producers.
Screenwriter Jae Matthews happens to be one half of the electronic music band Boy Harsher, which recently had songs on the soundtracks for the horror movies Terrifier 2 and Halloween Ends. Augustus Muller, the other half of the Boy Harsher duo, has composed the score for the film.
Does My Animal sound like a movie you’ll be watching in September? Are you glad to hear it has secured an R rating? Share your thoughts on this one by leaving a comment below.
Originally published at https://www.joblo.com/my-animal-r-rating/
LOS ANGELES, August 10, 2023 (Newswire.com) - On July 29, Los Angeles Mission, in collaboration with foster agencies Guardians of Love, Coco's Angels, and Inner Circle, launched its Third Annual Back-to-School Fair & Supply Giveaway. The event, which took place at Iglesia Cristiana Sembrando Esperanza, supported over 350 foster families currently in the foster care system.
"Our deepest desire is to ignite a spark of joy and readiness within the hearts of these children so they can eagerly embrace the arrival of the new school year," said Pastor Troy Vaughn, President and CEO of Los Angeles Mission. "Every student deserves to step into their educational journey with a heart filled with hope and the essential tools to thrive, irrespective of their financial circumstances."
The presenting sponsor CVS Health made a generous check presentation of $50,000. This gift will help kick-start mental health services at Los Angeles Mission and increase access for children and families experiencing homelessness in Los Angeles County. The Project Health mobile van provided by CVS Health also helped make it an extra-healthy occasion, offering free physical and mental health screenings to those most vulnerable Angelenos. This donation is more than just a financial gift; it's a symbol of hope for the community.
"The Los Angeles Mission is such an incredible organization, working to ensure equitable access to the support and resources children and their families need to thrive," said Jeff Hermosillo, West Region President, Aetna, a CVS Health company. "We are helping to increase their impact to support the launch of Los Angeles Mission's mental health services program because we believe high-quality mental health services should be available to everyone and that mental health is just as important as physical health."
This resource fair featured free clothes, shoes, backpacks, food, school supplies, music, haircuts, manicures, and a range of activities for kids ages 0-17. Target, which set up a bespoke shopping experience, mobilized 50 employee volunteers to distribute much-needed back-to-school supplies.
"As parents, it is heartbreaking to witness the struggles that children in foster homes face when it comes to their education," noted Kinikki Fullerwood, CEO of Guardians of Love. "Many of these precious kids dread going to school due to the lack of brand-new clothes or trendy items, fearing they will be singled out or bullied. The Back-to-School Fair aims to uplift and support these children, providing encouragement and igniting a flame of motivation within them, allowing them to thrive academically."
Race To Feed is a program launched by Los Angeles Mission in October 2021. It is a response to food insecurity which helps individuals stabilize and reinvest resources in their communities. Since its inception, this program has provided over four million meals to struggling families across L.A. County. Through this program, attendees left the back-to-school event with a full week of groceries.
Vaughn concluded by stating "The Los Angeles Mission is grateful to all of our partners, including Supervisor Hilda Solis, Walmart, Chick-Fil-A, CVS Health, Project Health, Target, Guardians of Love, Coco's Angels, and Inner Circle, who together made this event a major success."
For more information about Los Angeles Mission or this event, please contact Ellis McGinnis at [email protected].
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The late William Friedkin’s The Caine Mutiny Court-Martial starring Kiefer Sutherland will play at the Venice Film Festival.
Earlier today, the world lost one of Hollywood’s most influential filmmakers, William Friedkin. As condolences and wishes for peace pour in from family, friends, co-workers, and fans, we’d like to remind everyone that Friedkin’s final work, The Caine Mutiny Court-Martial, is heading to this year’s Venice Film Festival.
The annual festival continues despite the ongoing WGA and SAG-AFTRA strikes, with films by Richard Linklater, Wes Anderson, and Bradley Cooper also hitting the scene. The Caine Mutiny Court-Martial arrives as part of the festival’s non-competition program. Inspired by Herman Wouk’s classic novel The Caine Mutiny, the story takes place during World War II. The tale follows a young man who joins the Navy and ends up on a minesweeper in the Pacific. When the commanding officer shows signs of becoming unhinged, the XO takes command but is later court-martialed for mutiny.
This new version of The Caine Mutiny will give the story a contemporary spin. “The original piece was written for WWII, and Wouk included all the pent-up anger in this country over Pearl Harbor,” Friedkin told Deadline in 2022. “I’ve updated it so that is no longer Pearl Harbor. I’ve made it contemporary, involving the Gulf of Hormuz and the Straits of Hormuz, leading to Iran.” William Friedkin updated the script himself and knew that Kiefer Sutherland was the man to play Lt. Commander Queeg. “I think he is one of the best actors in America, one of the very best,” Friedkin said. “I saw every episode of his show 24. I thought he was just great but that he could do a lot more, and this gives him an opportunity to stretch.”
In addition to Friedkin’s The Caine Mutiny Court-Martial, the Venice Film Festival is hosting Maestro, the Bradley Cooper-directed biopic of Leonard Bernstein, Michael Mann’s race-car drama Ferrari, and David Fincher’s The Killer, a hitman drama starring Michael Fassbender. Sofia Coppola’s Priscilla, Yorgos Lanthimos’ Poor Things, and Ava DuVernay’s Origin also join the Golden Lion competition. Other selections include films by Roman Polanski and Woody Allen.
Are you interested in Friedkin’s final film? Let us know in the comments section below.
Originally published at https://www.joblo.com/the-caine-mutiny-court-martial-venice-film-festival/
No Hard Feelings: Digital, Blu-ray, and DVD details announced for Jennifer Lawrence’s raunchy comedy
Originally published at https://www.joblo.com/no-hard-feelings-digital-relea/
IRVING, Texas, August 10, 2023 (Newswire.com) - RideNow Experiences, a trailblazer in the vehicle rental service industry and a subsidiary of RideNow Powersports — the leading powersports dealer group in the United States — is thrilled to announce the opening of its services in three high-demand locations across the nation.
The decision to launch this innovative brand in Las Vegas, Atlanta, and Daytona Beach is a strategic move to cater to travelers who are seeking to enrich their vacation experience with the exhilaration of a powersports vehicle rental or tour. Each of these locations offers unique scenic routes and attractions that can be fully appreciated from the vantage point of a high-performance powersports vehicle.
RideNow Experiences not only provides premium powersport vehicle rentals but also looks to expand with self-guided tours, allowing customers to explore some of the best scenic spots these cities and their surrounding areas have to offer, thereby elevating their overall travel experience.
The fleet, comprised of pristine Slingshot® AutoDrive vehicles and Indian Motorcycles®, enables customers to create unique journeys and fully immerse themselves in exhilarating adventures.
In a breakaway from traditional rental industry practices, RideNow Experiences showcases a commitment to transparency, offering clear-cut pricing with no hidden fees. Coupled with value-added services such as 24/7 roadside assistance and unlimited mileage, customers are set for a hassle-free adventure on the open road.
Safety and comfort are paramount at RideNow Experiences. Every rental includes custom RideNow-branded eyewear and a helmet, ensuring riders can enjoy their adventure with peace of mind and a flair of style.
"Our goal is to provide an unparalleled experience for adventure seekers and travel enthusiasts," said Rocco Falabella, Director of RideNow Experiences. "With this service, we're not just providing extraordinary vehicles for rent; we're offering a gateway to memorable, worry-free explorations."
For additional information, visit www.ridenowrentals.com or connect with RideNow Experiences on social media.
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PITTSBURGH, August 10, 2023 (Newswire.com) - ST Engineering Aethon Inc. (Aethon), a leading provider of autonomous mobile robot solutions, today announced its inaugural RoboHero Award recipients. This award recognizes healthcare organizations that have achieved excellence in the adoption and utilization of mobile robotic technology as part of their operations.
"We are fortunate to have a long list of healthcare customers that rely on Aethon's autonomous mobile robots every day. This award recognizes the very top of this prestigious class for their consistency and leadership in deploying mobile robotic technology. We appreciate their dedication to our products, but most of all we value their partnership in helping to advance the use of our robots across their organizations," said Peter Seiff, CEO of ST Engineering Aethon.
"The Aethon robot has been a great team member for our laboratory. It has become an indispensable part of our operation, and this is a wonderful recognition of our lean workflow transformation and the efficiency gains produced," said Sarah Province, Laboratory Director at AdventHealth Orlando.
Recognitions are in the categories of 'Most Miles Traveled' and 'Most Deliveries Made' for a single robot within the following clinical and logistics departments throughout the hospital: Pharmacy, Laboratory, Nutrition, Surgical, Linen, Environmental Services, Materials, and Shared Use, for the June 1, 2022, to May 31, 2023, time period. In addition to individual departments, Aethon has recognized the top fleet customer in each category. A fleet customer is a hospital site using five or more robots. Each award recipient will receive a commemorative trophy from Aethon. In addition, all award recipients will be part of a draw where Aethon will select one recipient at random to donate $5,000 to a charity of its choice.
Most Miles Traveled for a Single Robot
Most Deliveries Made for a Single Robot
Top Fleet - Miles Traveled
Top Fleet - Deliveries Made
Across its customer base, Aethon's robots make millions of deliveries traveling hundreds of thousands of miles each year. Since 2004, Aethon robots have been a reliable, safe, and efficient solution for the movement of goods throughout hospitals around the world.
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About ST Engineering Aethon
ST Engineering Aethon is a leading provider of autonomous mobile robot solutions, dedicated to transforming the way organizations deliver goods. Aethon's innovative robots enhance operational efficiency, reduce costs, and improve overall productivity in both healthcare and hospitality verticals. By leveraging cutting-edge technologies, including artificial intelligence, machine learning, and advanced navigation systems, Aethon empowers organizations to optimize internal logistics and free up resources for higher-value activities.
About ST Engineering
ST Engineering is a global technology, defense and engineering group with a diverse portfolio of businesses across the aerospace, smart city, defense and public security segments. The Group harnesses technology and innovation to solve real-world problems, enabling a more secure and sustainable world. Headquartered in Singapore, it has operations spanning Asia, Europe, the Middle East and the U.S., serving customers in more than 100 countries. ST Engineering reported revenue of about US$6.8b in FY2022 and ranks among the largest companies listed on the Singapore Exchange. It is a component stock of the FTSE Straits Times Index, Dow Jones Sustainability Asia Pacific Index, iEdge SG ESG Transparency Index and iEdge SG ESG Leaders Index.
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