The research will enable millions of people to use facemasks and protect their face from facemask-related complications

SURREY, British Columbia - November 1, 2022 - (Newswire.com)

A clinical research study has shown that facial topical cream promotes facemask tolerability and compliance during the COVID-19 pandemic. The reputable research was led and authored by Dr. Olumuyiwa Bamgbade at the Salem Anaesthesia Pain Clinic in Surrey, British Columbia, Canada. 

Dr. Bamgbade is an anesthesiologist, assistant professor and specialist pain physician who trained in Nigeria, Britain, USA, France and South Korea (https://www.linkedin.com/in/olu-bamgbade-frcpc-md-pain-med-diploma-msc-baa79b18b/). Dr. Bamgbade is the director of the Salem Anaesthesia Pain Clinic, a specialist pain clinic and research center (https://salempainclinic.net/). The clinical research was published in the Journal of Taibah University Medical Sciences: https://doi.org/10.1016/j.jtumed.2021.12.012. 

Facemask use is associated with localized facial skin complications such as rash, bruising, acne, itching, discomfort, discoloration, redness, hotness, ulceration, crusting, infection, and dermatitis. Such complications may provoke face-touching, face-scratching and facemask non-compliance, which undermines facemask protective efficacy and COVID-19 infection control. Therefore, the research study examined the impact of different non-prescription topical creams on facemask tolerability, facemask compliance and related skin complications during the COVID-19 pandemic. Six topical creams were evaluated including petrolatum jelly, hydrocortisone cream, lidocaine gel, zinc oxide cream, arnica cream and diphenhydramine cream.

"The study revealed that all the topical creams reduce facemask-related facial redness, facial temperature rise, and facial pain. Facial temperature rise is lowest with topical lidocaine gel; early facial redness is lowest with topical hydrocortisone or diphenhydramine cream; severe facial redness is lowest with topical hydrocortisone or zinc oxide cream; and facemask-related pain is lowest with topical lidocaine gel," explained Dr. Bamgbade. "All the topical creams reduce facemask-related skin complications, and thereby enhance facemask compliance and tolerability. Facemask compliance is best with topical lidocaine gel. Topical petrolatum jelly has the best user satisfaction and odor rating. People who wear facemasks frequently or for prolonged duration should protect their skin with topical petrolatum, zinc oxide or arnica cream. People who experience facial redness from facemasks should treat their skin with topical hydrocortisone or diphenhydramine cream," advised Dr. Bamgbade. "People who experience significant facemask-related facial pain may use topical lidocaine gel."

Based in Surrey, British Columbia, Canada, Salem Anaesthesia Pain Clinic is a specialist pain clinic and research center that provides multimodal pain management, interventional pain treatment, substance misuse therapy, insomnia treatment and preoperative optimization therapy. Dr. Olumuyiwa Bamgbade is an anesthesiologist, a specialist pain physician and the director of the Salem Pain Clinic. Visit https://salempainclinic.net/. For further information: [email protected].

Contact Information:
Olu Bamgbade
Medical Director
[email protected]
+17786286600
Related Files
Olu Bamgbade Publications. Google Scholar Oct2022.pdf



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Original Source: Research by Dr Bamgbade and Salem Pain Clinic Canada, Shows That Facial Topical Cream Enhances Facemask Tolerability and Compliance During COVID-19 Pandemic

Leading podiatrist in Wayne, New Jersey, partners with the Ankle & Foot Centers of America, the nation's leading group of foot and ankle surgeons. This relationship allows doctors to dedicate their time to treating patients instead of administrating a podiatry practice.

WAYNE, N.J. - November 1, 2022 - (Newswire.com)

Renown New Jersey podiatrist Lindsey Calligaro, DPM, of Wayne Foot & Ankle Center has recently teamed with Ankle & Foot Centers of America, the market leader in physician practice management and process improvement, to better serve patients. Wayne Foot & Ankle Center has been providing the highest-quality care to patients for over 40 years, and is dedicated to improving the lives of people in the northern NJ community.

Dr. Lindsey Calligaro earned her Doctor of Podiatric Medicine from the New York College of Podiatric Medicine in 2011 and attended a comprehensive three (3) year residency in Scranton, Pennsylvania with Dr. Guido LaPorta. Dr. Calligaro served as Chief Fellow during her fellowship in Baltimore, Maryland, at the Rubin Institute for Advanced Orthopedics/International Center for Limb Lengthening. Dr. Calligaro's training specialized in complex foot and ankle deformity correction and pediatric deformity correction. Dr. Calligaro treats a variety of foot and ankle problems, including bunions, heel pain, trauma, and flatfeet. She also specializes in all aspects of pediatric foot and ankle deformity correction with a special interest in clubfoot. Helping to serve the needs of patients is what brought Dr. Calligaro to podiatry, and it is what motivates her to provide the best care possible every day.

Teaming with Ankle & Foot Centers of America allows physicians like Dr. Calligaro to do what they do best, take care of patients. With Ankle and Foot Centers of America, Dr. Calligaro is now able to benefit from the most advanced software, reporting, and office support in the industry. As healthcare becomes more complicated with technology and regulation, physicians must rely on expert support.

Incorporating the central scheduling team and call center from Ankle and Foot Centers of America allows patients to make appointments with greater ease with this Wayne, NJ, Podiatrist. Whether booking online or over the phone, patients can now expect to have a more streamlined experience. Additionally, Ankle and Foot Centers of America incorporates advanced network safeguards to better protect patient data and provides new training for staff on the latest advances and changes in healthcare.

With a shared commitment to excellence and dedication to patient well-being, Dr. Calligaro and the team at Ankle and Foot Centers of America look forward to treating the foot and ankle needs of patients in north New Jersey.

About Ankle & Foot Centers of America - Founded in Atlanta over 30 years ago, Ankle & Foot Centers of America is dedicated to providing patients with top-tier service and support through best-in-class technology and processes so that physicians can optimize patient outcomes and satisfaction.

Contact Information:
Alexis Pickford
Marketing Representative
678-561-9000


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Original Source: New Jersey Podiatrist Teams with Ankle & Foot Centers of America

As published in the journal Food and Chemical Toxicology, the biopharmaceutical drug development firm's sponsored research used co-cultured human, primary immune cells as a model to evaluate the ability of selected Cannabis constituents to decrease inflammation.

LAS VEGAS - November 1, 2022 - (Newswire.com)

Gb Sciences, Inc. (OTCQB:GBLX), a leading plant-inspired, biopharmaceutical research and drug development company, has co-published a study in the journal Food and Chemical Toxicology that demonstrates the potential of selected cannabinoids and terpenes to reduce inflammation. Finding Cannabis compounds with anti-inflammatory properties may be useful in decreasing inflammation associated with a wide range of serious human disorders, and these Cannabis compounds potentially have more favorable side effect profiles than NSAIDs (Non-Steroidal Anti-Inflammatory Drugs), which currently lead the anti-inflammatory market based on sales. Largely because of the increasing prevalence of chronic and auto-immune inflammatory disorders, the market for anti-inflammatory therapies is expected to grow to $191.42 billion by 2027.

"We believe that this is the first demonstration of the anti-inflammatory potential of some very potent minor cannabinoids and terpenes derived from Cannabis," said Dr. Andrea Small-Howard, President, Chief Science Officer, and Director of Gb Sciences. "The identification of cell type-specific immune modulating effects by different individual cannabinoids and terpenes was an important first step in designing our novel anti-inflammatory therapies. The results from our second study on the anti-inflammatory effects of proprietary mixtures of these ingredients will be published subsequently with our collaborators at Michigan State University and Chaminade University."

Gb Sciences selected the specific Cannabis constituents for this study based on their prior activity within chemovar studies. To determine whether these cannabinoids and terpenes could reduce inflammation, Gb Sciences' colleagues at Michigan State University tested the individual Cannabis constituents over a wide range of concentrations in human, primary immune cells in a co-culture system that mimics the complex interactions that regulate the human immune system. Three immune cell types were chosen as representatives within these native human immune cell mixtures based on their important roles in modulating the inflammatory cascade.

This study demonstrated that delta-9 tetrahydrocannabinol (THC) had the greatest effect on reducing inflammatory biomarkers and processes in all three immune cell types. Following THC, the greatest immune activity modulation was measured by cannabidivarin (CBDV), cannabigerol (CBG), cannabichromene (CBC), cannabinol (CBN), and lastly, cannabidiol (CBD) in decreasing order based on the number of statistically significant changes measured in inflammatory bioassays relative to the control. Some of these minor cannabinoids and the terpenes tested had very 'selective' anti-inflammatory effects, which targeted a single cell type and/or caused a change in only a single inflammatory bioassay.

This study entitled "Evaluation of the anti-inflammatory effects of selected cannabinoids and terpenes from Cannabis Sativa employing human primary leukocytes" was co-authored by Gb Sciences' own President and Chief Science Officer, Andrea Small-Howard, and her collaborators Lance K. Blevins, Anthony P. Bach, Robert B. Crawford, Jiajun Zhou, Joseph E. Henriquez, Michael D. Rizzo, Sera Sermet, D.M. Isha Olive Khan, and Norbert Kaminski from Michigan State University (East Lansing, Michigan, USA) and Helen Turner from Chaminade University of Honolulu (Honolulu, Hawai'i, USA). The second part of this study measured the effects of proprietary mixtures of cannabinoids and terpenes on inflammation within this human, primary immune cell model, and this second study will be published next in collaboration with our colleagues at Michigan State University and Chaminade University.

To learn more about Gb Sciences, visit www.gbsciences.com.

About Gb Sciences and GbS Global Biopharma

Gb Sciences, Inc. is a plant-inspired, biopharmaceutical research and development company creating patented, disease-targeted formulations of cannabis- and other plant-inspired therapeutic mixtures for the prescription drug market through its Canadian subsidiary, GbS Global Biopharma, Inc. The 'plant-inspired' active ingredients in its therapeutic mixtures are synthetic homologues identical to the original plant compounds but produced under current Good Manufacturing Practices. Gb Sciences' intellectual property portfolio contains six issued U.S. and three issued foreign patents, as well as 17 U.S. and 51 foreign patent-pending applications. In its drug development pipeline, Gb Sciences has five preclinical phase product development programs. Gb Sciences' lead program for Parkinson's disease is being prepared for a first-in-human clinical trial. Gb Sciences' formulations for chronic pain, anxiety, and depression are currently in preclinical animal studies with researchers at the National Research Council of Canada. The company also received positive preclinical proof-of-concept data supporting its complex mixtures for the treatment of Cytokine Release Syndrome related to COVID-19, and its lead candidates will be optimized based on late-stage preclinical studies at Michigan State University. Gb Sciences' productive research and development network includes distinguished universities, hospitals, and Contract Research Organizations. To learn more, visit www.gbsciences.com.

Forward-Looking Statements

This press release may contain statements relating to future results or events, which are forward-looking statements. Words such as "expects", "intends", "plans", "may", "could", "should", "anticipates", "likely", "believes" and words of similar import may identify forward-looking statements. These statements are not historical facts, but instead represent only the Company's belief regarding future events, many of which, by their nature, are inherently uncertain and outside of the Company's control. It is possible that the Company's actual results and financial condition may differ, possibly materially, from the anticipated results and financial condition indicated in these forward-looking statements. Further, information concerning the Company and its business, including factors that potentially could materially affect the Company's business and financial and other results, are contained in the Company's filings with the Securities and Exchange Commission, available at www.sec.gov. All forward-looking statements included in this press release are made only as of the date of this press release, and we do not undertake any obligation to publicly update or correct any forward-looking statements to reflect events or circumstances that subsequently occur or of which we hereafter become aware.

Contact Information:
Madeleine Moench
[email protected]


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Original Source: Gb Sciences Co-Publishes Study Demonstrating Anti-Inflammatory Properties of Cannabis Ingredients

CARY, N.C. - November 1, 2022 - (Newswire.com)

InstantGMP, the originators of the all-in-one manufacturing and quality system, is proud to welcome a new contract development and manufacturing organization, Quality Chemical Laboratories (QCL), to its growing client base.

Quality Chemical Laboratories was founded in 1998 as a raw material testing laboratory and has continuously expanded capabilities and service offerings. For over 25 years, this leading CDMO has provided GMP-compliant formulation development and manufacturing services for the pharmaceutical industry. The company's clients range from small start-up companies to some of the most prominent pharmaceutical corporations in the world.

As its client base continues to grow, Quality Chemical Laboratories recognized the importance of implementing a new software system to enhance its processes while gaining efficiency and maintaining GMP and FDA compliance.

QCL's exhaustive search for a new software system led the company to the InstantGMP PRO system. While the software's all-in-one capabilities impressed the QCL team, they required computer system validation to determine if the system:

• Meets FDA Part 11 compliance.
• Achieves its intended purpose by meeting user requirements.
• Is free from any installation or performance issues that could negatively impact the integrity of the CDMO's production cycles, raw materials or finished pharmaceutical products.

To ensure that the InstantGMP PRO system was validated, Quality Chemical Laboratories conducted an extensive software vendor audit. During the software vendor auditing process, QCL reviewed every piece of the software's validation documentation and standard operating procedures (SOPs) via a virtual session with InstantGMP to confirm that InstantGMP PRO:

• Is properly validated.
• Vendor documentation can be appropriately leveraged to save QCL significant time and resources.
• Functions accordingly and accurately.
• Aligns with the information defined in the provided user requirement documentation.

After QCL reviewed all the respective documentation and asked any pertinent questions, it created and supplied a detailed audit report that identified topics that required further discussion and some minor issues that needed to be resolved. At the conclusion of the audit process, InstantGMP successfully satisfied Quality Chemical Laboratories' requirements.

Not only did this process lead to a successful relationship, but it also provided the QCL team a better understanding of the software's full capabilities. Additionally, the audit process offered InstantGMP an opportunity to address previously unidentified issues and further enhance the software with new features that best meet manufacturers' needs.

InstantGMP is excited to provide Quality Chemical Laboratories with a validated all-in-one software system that truly meets its needs for improved processes and assured compliance. InstantGMP wishes them continued success in the contract formulation development and manufacturing industry and thanks them for helping InstantGMP enhance their software during the audit process.

To learn more about InstantGMP PRO's new features and software auditing processes for GMP manufacturers, contact us to schedule a demonstration.

Contact Information:
Robert Pochadt
Director of Sales
[email protected]
215-975-9660

Jeremy Hall
Technical Sales Manager
[email protected]
757-759-4500


Related Files
InstantGMP PRO for FDA Requlated Industries 4.22.pdf



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Original Source: New CDMO Client, Quality Chemical Laboratories, Benefits From InstantGMP's All-in-One Quality & Manufacturing System and Software Auditing for GMP Manufacturers

ZetrOZ's sam®️ technology promotes soft tissue healing, helping patients return to work sooner and preventing more severe injuries; the only FDA-cleared home-use multi-hour ultrasound stimulator.

TRUMBULL, Conn. - October 31, 2022 - (Newswire.com)

ZetrOZ Systems presented to the Michigan Self-Insurers Association 2022 Fall Conference on Oct. 27 about how the ZetrOZ sam® wearable ultrasound device helps patients return to work more quickly after soft-tissue injuries and prevents more severe injuries from occurring. 

ZetrOZ Systems has partnered with the organization of self-insured employers on ways to educate businesses on how to prevent and respond to workplace accidents and injuries. The sam® device has been shown in more than 30 clinical studies to deliver significant improvement in joint function, increased pain reduction, and improved vasodilation - all of which ultimately contribute to accelerated healing and increasing integrity of recovered soft tissue. The sam® product line is also shown to mitigate pain from soft-tissue injuries in the upper neck and back, shoulder conditions, and knee osteoarthritis. 

"sam® is already helping thousands of lives daily, and we're honored to be partnering alongside MSIA and the self-insured businesses in Michigan to provide effective treatment for workplace injuries," said Dr. George Lewis, CEO of ZetrOZ Systems. "It's incredibly important to us to help treat workers' injuries, relieve pain, improve long-term outcomes, and ultimately, get people back to work sooner."

Statistics show a need for better care for the workforce, particularly at self-insured workplaces. American workers experienced 2.1 million injuries in 2020, according to the U.S. Bureau of Labor Statistics, and 82% of workers at large firms were covered by self-funded insurance plans in 2021. 

There also is a need for effective pain relief without potentially addictive and dangerous medications. The United States spends about $1 trillion on opioid use disorder and fatal opioid overdoses (2018, Centers for Disease Control and Council of Economic Advisors). Innovations like the sam®x1  pain relief ultrasound device provide wireless, long-duration ultrasound therapy for injury healing and pain relief without medication.

The Michigan Self-Insurers' Association [MSIA] is a non-profit organization founded in 1952 that has worked tirelessly over the last 70 years to educate self-insured employers on workers' compensation issues. With the goal of reducing and ultimately preventing workplace accidents and injuries, MSIA and sam® are uniquely aligned to empower workers with the tools and resources to protect themselves and their livelihoods. 

MSIA's Board of Managers includes DTE, Meijer, Marathon Oil, and representation from many other self-insured employers, and the organization has been a proud partner of Kids' Chance of Michigan since 2013.

"Our sam® product portfolio offers patients a way to mitigate and reduce workplace injury and pain without resorting to opioids or nonsteroidal anti-inflammatory drugs, which have shown to potentially harm more than they help. Now, these hard-working men and women have a chance to safely and properly heal in the comfort of their own homes," Lewis said. 

To learn more, visit zetrozsystems.com.  

About ZetrOZ Systems

ZetrOZ Systems is leading healing innovations in sports medicine and developing wearable bioelectronic devices for the delivery of sustained acoustic medicine (sam®). Researched and funded by the federal government, ZetrOZ is built on proprietary medical technology of +46 patents and is the exclusive manufacturer and developer of sam®, a product line designed for the treatment of acute and chronic musculoskeletal conditions. To learn more, visit zetrozsystems.com.

Contact Information:
Buse Kayar
[email protected]


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Original Source: ZetrOZ Partners With Michigan Self-Insurers Association to Educate on Sustained Acoustic Medicine for Workplace Injury Healing

Fusion Marketplace is taking every step possible to make sure healthcare professionals feel supported while they navigate their careers.

OMAHA, Neb. - October 31, 2022 - (Newswire.com)

Fusion Marketplace, a traveler-first driven platform aimed at making the job search for healthcare professionals simple, is cultivating a healthy discussion and support for travelers experiencing hardships. 

New research published by the American Association of Nurse Anesthesiology shows that it's common for healthcare professionals to experience secondhand trauma when treating patients who have experienced critical events. This phenomenon refers to the healthcare professional as a second victim of the trauma. Research says it's important for those healthcare professionals to have someone who will actively and empathetically listen to their experiences.

Travel healthcare can be a lonely profession if the traveler doesn't have a support system they can lean on. Having short contracts at facilities can make it hard to develop relationships and deep connections with their peers, but Marketplace is fixing that.

"Fusion Marketplace is here to support the travelers that use it, and that goes deeper than simply helping them find their next assignment," said Steve Koesters, Fusion Marketplace President. "The platform encourages and cultivates conversation between travelers about the hard topics so they know they have a community to lean on."

Through online support groups and an open door to reach out to people on the Fusion Marketplace team, travelers on the platform always have an ear and someone to turn to when they need it.

In addition to those support groups, Marketplace is also making it easier for travelers to navigate their career, ultimately giving them more time for relaxation, self-care, hobbies, family time, and anything else that helps prevent burnout. 

To learn more about Fusion Marketplace and to create a traveler profile, go to fusionmarketplace.com or download the Fusion Marketplace app, available now in the App Store and Google Play Store.  

About Fusion Marketplace:  

Fusion Marketplace is a staffing recruitment platform where healthcare travelers are in control. Healthcare travelers now have more career, agency, recruiter, and lifestyle choices in one convenient location. Unknowns known. Learn more at fusionmarketplace.com.

Contact Information:
Leah Kemple
Public Relations Specialist
[email protected]
4025755625


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Original Source: Healthcare Job Platform Cultivates Support and Conversation Among Travel Healthcare Professionals

CAMBRIDGE, Mass. - October 31, 2022 - (Newswire.com)

Nominations are opening soon for the first award of the Richard N. Merkin Prize in Biomedical Technology, which recognizes novel technologies that have improved human health. 

About the Merkin Family Foundation

The Merkin Family Foundation was founded by visionary healthcare executive Richard Merkin, MD.

Richard Merkin, MD, is the founder and CEO of Heritage Provider Network, Inc. (HPN). HPN is the largest physician-owned managed care organization in the country dedicated to value-based healthcare delivery improvements. HPN develops and manages coordinated, patient-doctor centric, integrated healthcare systems that offer some of the strongest solutions for the future of health, care, and cost in the United States. HPN and its affiliates operate in New York, California, Arizona, and Colorado, providing high-quality, cost-effective healthcare with over one million patient members. HPN is dedicated to quality, affordable healthcare, and putting patients' wellness first.

About Broad Institute of MIT and Harvard

Broad Institute of MIT and Harvard was launched in 2004 to empower this generation of creative scientists to transform medicine. The Broad Institute seeks to describe the molecular components of life and their connections; discover the molecular basis of major human diseases; develop effective new approaches to diagnostics and therapeutics; and disseminate discoveries, tools, methods, and data openly to the entire scientific community.

Founded by MIT, Harvard, Harvard-affiliated hospitals, and the visionary Los Angeles philanthropists Eli and Edythe L. Broad, the Broad Institute includes faculty, professional staff, and students from throughout the MIT and Harvard biomedical research communities and beyond, with collaborations spanning over a hundred private and public institutions in more than 40 countries worldwide.

Contact Information:
Nick Puleo
[email protected]


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Original Source: Launch of the Merkin Prize in Biomedical Technology