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Travel Expert Rachel Rudwall Shares Why Fall Travel Should Top Every To-Do List on TipsOnTV

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Travel Expert Rachel Rudwall Shares Why Fall Travel Should Top Every To-Do List on TipsOnTV
Great Tips on Getaways and Gadgets to Fill Fall with Hassle-Free Adventure


Travel Expert Rachel Rudwall Gives Fall Getaway Ideas

National Geographic Explorer Rachel Rudwall Shares Tips for Traveling this Fall

Fall is the perfect time to plan a getaway or vacation, with unique and affordable options unavailable during the crowded summer. With the kids back in school and moderate weather, this time of year is a fantastic, less expensive, and pleasant time to get away. TV host and travel expert Rachel Rudwall has essential travel tips and best-kept secrets for finding terrific deals and destinations. Whether looking for the top places to enjoy fall foliage or a quick beach vacation, here are some easy hacks to save time and money.

MAKE IT EASIER TO TRAVEL

Start with power. Yoshino’s innovative technology brings a premium compact portable power solution to everyday life. Easily power activities around the house like outdoor movie night. Take it camping or RVing and power lights and devices, or keep phones, laptops and camera batteries charged during a road trip. Simple to charge, it provides up to 660 watts of power through AC, DC and USB outlets. Also, use Yoshino as a solar generator with the optional solar panels and generate power while camping or off-grid. For more information, visit yoshinopower.com.

A FAVORITE FALL DESTINATION

Michigan is home to two spectacular peninsulas that offer the freshest places to see fall colors. Each fall, the state’s 19 million acres of forest come alive with a crescendo of brilliant oranges, yellows and reds, creating the perfect backdrop for a scenic drive, refreshing trail hike, or a visit to an apple orchard or cider mill. Fall also means football season. Check out a college game in towns like Ann Arbor or East Lansing, or head to Ford Field for a pro game in Detroit where the 2024 NFL Draft is being hosted. Plan a trip at www.Michigan.org.

FINDING A GREAT PLACE TO STAY

When looking for a great place to stay, Rachel recommends the Trademark Collection by Wyndham. They have one-of-a-kind hotels in amazing destinations all over the world, plus a number of incredible properties in gaming destinations as part of their partnership with Caesars Entertainment. Think of hotels with luxurious spas, and celebrity chef-inspired dining in cities like Las Vegas, Atlantic City and New Orleans. Best of all, earn Wyndham Rewards points with every stay, getting that much closer to the next free trip! Head over to TrademarkHotels.com for all the details. 

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TipsOnTV covers a variety of topics, including food, entertaining, personal finance, technology, travel, health, lifestyle and more.

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Original Source: Travel Expert Rachel Rudwall Shares Why Fall Travel Should Top Every To-Do List on TipsOnTV

Travel Expert Carmen Ordonez Shares Tips to Celebrate Hispanic Heritage on TipsOnTV

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Travel Expert Carmen Ordonez Shares Tips to Celebrate Hispanic Heritage on TipsOnTV
Learn More About the Trends and Traditions that Make this Month Special in Florida


Travel & Lifestyle Expert Carmen Ordonez Shares Highlights of Hispanic Heritage Month in Florida

Lifestyle Journalist Carmen Ordonez Offers Ideas for Celebrating Hispanic Heritage Month in 'La Florida'

Florida, fondly known as “La Florida,” has a profound connection to Hispanic culture that dates back centuries, and this month-long celebration is a perfect opportunity to explore and honor the diverse traditions, history, and contributions of the Hispanic community throughout the Sunshine State. On September 14, Travel Expert and Founder of Viva Fashion, Carmen Ordonez, partnered with VISIT FLORIDA to showcase the rich culture, delectable cuisines, and enchanting destinations. Find out about the vibrant spectrum of Hispanic heritage and traditions flourishing across the diverse landscapes of Florida.

HISPANIC HERITAGE MONTH

Hispanic Heritage Month takes place every year to honor and celebrate the cultures, contributions, and extensive histories of Hispanic Americans. For one month every year, September 15 through October 15, Hispanic Heritage Month is celebrated nationwide through festivals, art shows, conferences, community gatherings and much more. They routinely highlight the best destinations that offer Hispanic culture, cuisine, and events. As a Floridian, Carmen can attest to the fact that Florida offers all three not just during Hispanic Heritage Month, but all year round.

CONSIDER THE CULTURE WHEN CHOOSING A PLACE TO VACATION

If travelers are looking to connect with a community and with people who live in a specific destination, they need to understand where they come from, their culture and their traditions. This allows them to get a sense of unique experiences they can look forward to and expect while there, such as authentic cuisine the area is known for or attractions that bring the destination’s rich history to life. From delightful flavors of Latin cuisine to mesmerizing art and music, there is a complete cultural journey across the Sunshine State, honoring the Hispanic community that has had a significant and lasting impact on the state.

CELEBRATE HISPANIC HERITAGE

The influence of Hispanic culture is deeply ingrained in Florida’s rich history, and its legacy is evident across Florida today, as the state is home to the third-largest Latino population in the country. During Hispanic Heritage Month, travelers can experience lively parades, colorful festivals, captivating exhibitions, and educational seminars, designed to enrich the understanding of the Hispanic community and its importance to Florida’s identity. 

OTHER WAYS TO EXPERIENCE THIS CULTURE

There is a wide variety of Hispanic cultures and traditions across Florida today, reflecting the state’s cultural mosaic, from salsa dancing in Miami or Orlando to cigar-rolling in Tampa’s Ybor City, Little Havana in Miami, or Key West. Stroll down the cobblestones of St. George’s Street in historic St. Augustine or discover the mastery of the renowned Spanish artist Salvador Dali at the Salvador Dali Museum in St. Petersburg. A trip must also include Mojitos in Little Havana or experiencing the passion and energy of Flamenco shows in Miami, Tampa, or St. Augustine.

For more information, visit www.VISITFLORIDA.com/HispanicHeritage.

About VISIT FLORIDA

VISIT FLORIDA is the Sunshine State’s official tourism marketing corporation and travel planning resource for visitors across the globe. As Florida’s No. 1 industry, tourism was responsible for welcoming over 137.6 million visitors in 2022, the highest number of visitors in the state’s history. VISIT FLORIDA promotes tourism through sales, advertising, promotions, public relations, and visitor services programs, and serves more than 13,000 travel industry partners throughout the state. To learn more about VISIT FLORIDA, follow @FloridaTourism on Facebook and Twitter, or go to visitflorida.org. For inspiration in the Sunshine State, follow @VISITFLORIDA on Facebook, Twitter and Instagram or visit www.visitflorida.com. For media resources, visit www.visitfloridamedia.com.

About TipsOnTV 

TipsOnTV covers a variety of topics, including food, entertaining, personal finance, technology, travel, health, lifestyle and more.

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Original Source: Travel Expert Carmen Ordonez Shares Tips to Celebrate Hispanic Heritage on TipsOnTV

CONQUERing Unveils Revolutionary Fidget Jewelry Designs Amid Sensory Processing Awareness Month

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CONQUERing Unveils Revolutionary Fidget Jewelry Designs Amid Sensory Processing Awareness Month
Trailblazing Fashion Brand Expands Collection With Soothing Tactile Patterns, Offering a Stylish Respite for Individuals With Sensory Processing Disorders.


CONQUERing interchangeable fidget jewelry sensory processing rings

Silver ring band with 3 interchangeable sensory discs

CONQUERing® today announced the release of three new jewelry designs in its line of interchangeable fidget jewelry to raise awareness during Sensory Processing Awareness Month in October. The three new designs each have a soothing tactile pattern: waves, ridges, and bumps.

Recognized as a trailblazer in the adaptive-fashion movement by Fashion Magazine, it comes as no surprise that CONQUERing would, again, innovate new ways to support those with different abilities. CONQUERing jewelry is already enjoyed by many with Sensory Processing Disorders due to its unique spinning and clicking capabilities – perfect for discreet fidgeting on the go. The new collection furthers the sensory support with interchangeable tactile discs.

CONQUERing customer Alysia Tomczyk shared, “As someone that has struggled with their sensory processing disorder, having my CONQUERing helps me daily! These new specially-designed tactile spinners help increase or decrease my sensory input as I need it without making it evident.”

Sensory Processing Disorders are more common in adults and children than many people realize. In fact, a study published on the National Institutes of Health website estimates that as much as 16.5% of the general population have symptoms associated with sensory processing challenges.

CONQUERing Founder & CEO, Tammy Nelson, shared, “Whether it through offering an expansive size range, supporting marginalized groups or providing products for those with different abilities, we aim to be inclusive. This is just one more way we support our customers to help them conquer their day, as we like to say.”

In celebration of the launch of these distinctive sensory designs over the upcoming weekend, CONQUERing is thrilled to present a complimentary Calm Strips® duo to those acquiring the set. Calm Strips are discreet, portable sensory stickers with a textured surface, another tool for use in overwhelming settings.

To learn more about CONQUERing, visit www.myconquering.com and follow the brand on TikTokInstagram, and Facebook.

Contact Information:
Alisha Molloy
Business Manager
[email protected]
513-216-5222


Original Source: CONQUERing Unveils Revolutionary Fidget Jewelry Designs Amid Sensory Processing Awareness Month

Curated Mental Health Drives Mental Health Awareness Through September Yellow Campaign

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Curated Mental Health Drives Mental Health Awareness Through September Yellow Campaign

In 2022, a staggering 49,449 Americans lost their lives to suicide, underscoring the urgent need to address mental health challenges. With this in mind, during the month of September, Curated Mental Health launched the "September Yellow" campaign as a powerful reminder of the unwavering commitment to fostering understanding, empathy, and support for individuals facing the complexities of mental health. 

The color yellow, symbolizing hope and renewal, lies at the heart of this campaign. It encapsulates the journey toward mental well-being and the resilience that individuals possess when confronted with mental health challenges. As part of the "September Yellow" campaign, Curated is actively sharing practical and accurate information about mental health on its social media platforms. 

To ensure that those in need have access to information, the mental health practice is offering complimentary discovery calls. These calls are intended to assist individuals who haven't achieved the desired results with traditional medications and are seeking to embark on their healing journeys; gathering sufficient information is a crucial first step on this transformative path. 

These initiatives aim to encourage individuals to prioritize their mental well-being and are a testament to the dedication to making mental health care accessible to all. 

For more information about Curated Mental Health's "September Yellow" campaign and to schedule a free discovery call with Curated's psychedelic liaison, please visit www.curatedmentalhealth.com or contact (917) 451-7018. 

Contact Information:
Amanda Mamede
PR Manager
[email protected]
9294905525


Original Source: Curated Mental Health Drives Mental Health Awareness Through September Yellow Campaign

Exclusive: Mr. & Mrs. Smith sequel never happened due to lack of a strong plot

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Exclusive: Mr. & Mrs. Smith sequel never happened due to lack of a strong plot

Despite making nearly $500 million worldwide, Mr. & Mrs. Smith never got a sequel. We spoke to the writer and found out why.

Mr. & Mrs. Smith has to be one of the biggest movies never to get a sequel. Having grossed nearly $500 million worldwide, a follow-up would have seemed like a no-brainer. Filmed during happier times for the now divorced Brad Pitt and Angelina Jolie, the movie starred the gorgeous pair as sexy married spies who think their occupations are secret from their unknowing spouse. Assigned to kill each other, when they start fighting, they find the spark their marriage has been missing, and they team up to take on their crooked handlers.

According to the movie’s writer, Simon Kinberg, whom I spoke to recently via Zoom, there was a notion to do a sequel, but no one could figure out how to follow up the relatively close-ended story. “The strength of the first movie is it’s a love story; they are, you know, falling back in love with each other or in love for the first time in a genuine way. And to tell a love story, to serialize a love story is very hard. Because no matter what you do in the second movie, sure, they could be partners and spies and bickering together, but you wouldn’t actually have the arc of two people who are falling in love.”

After experimenting with various plot points, including having them partner up or get separated, the sequel idea was abandoned. While it never happened, a Mr. & Mrs. Smith series for Prime Video starring Donald Glover is set to launch soon. Director Doug Liman is also dipping his toes back into action films, shooting the highly anticipated Road House remake with Jake Gyllenhaal, which recently nabbed an R-rating. Meanwhile, Simon Kinberg’s Apple Plus show, Invasion, is wrapping its second season. Check it out – it’s a hidden gem.

https://www.youtube.com/watch?v=ftdbj2spu5g

Originally published at https://www.joblo.com/exclusive-mr-mrs-smith-sequel-never-happened-due-to-lack-of-a-strong-plot/

Infinx Healthcare Recognized as a Sample Vendor for Intelligent Prior Authorization for Second Year in a Row in the Gartner Hype Cycle for U.S. Healthcare Payers, 2023

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Infinx Healthcare Recognized as a Sample Vendor for Intelligent Prior Authorization for Second Year in a Row in the Gartner Hype Cycle for U.S. Healthcare Payers, 2023
Gartner Hype Cycle Recognizes Infinx Healthcare as a Sample Vendor for Intelligent Prior Authorization


Intelligent Prior Authorization

Gartner recognizes Infinx Healthcare

Infinx Healthcare, a leading technology-enabled revenue cycle solutions provider, announced today that it has been recognized as a Sample Vendor for a second year in a row for Intelligent Prior Authorization in the Gartner Hype Cycle for US Healthcare Payers in 2023.

Gartner Hype Cycle methodology gives a view of how a technology or application will evolve over time, providing a sound source of insight to manage its deployment within the context of an organization’s specific business goals. This Hype Cycle provides critical input for strategic planning by tracking the maturity level and adoption rate of payer technologies and deployment approaches. 

Intelligent Prior Authorization Received Transformational Benefit Rating

Intelligent Prior Authorization received benefit rating as Transformational in this year’s report. 

According to Gartner, “Intelligent prior authorizations (PAs) use APIs, NLP and AI to automate the decision making, data exchange and workflows between providers and payers to process requests for services while informing consumers of their PA status. Intelligent PAs include the automation of workflows by which a provider submits treatment notification for a payer’s review and the predictive process payers use to approve care. These tools reduce the high administrative burden associated with the process.”

Infinx Healthcare Named As a Sample Vendor For Intelligent Prior Authorization

Jaideep Tandon, Chairman and CEO of Infinx, said, “We believe this year’s listing in the Gartner Hype Cycle reinforces to healthcare executives how technologies powered by AI, automation, analytics and intelligent workforce management will define the future of revenue cycle management.”

“Healthcare providers and payers have many options when it comes to technology and applications,” said Tandon. “It’s confusing and challenging for the busy CIO to determine which technologies are worth the investment and how long it will take for a return on investment. We are pleased to be recognized by Gartner as a sample vendor for Intelligent Prior Authorization.” 

Accelerating Prior Authorizations Approvals with Infinx’s AI-Powered Patient Access Plus Platform

Provider clients rely on Infinx’s AI-powered Patient Access Plus platform to execute end-to-end prior authorization workflows that are optimized with payer and EHR integrations, AI, automation, intelligent workflow management and support from our in-house team of clinical specialists. With their technology-enabled solution, clients observe repetitive work performed by their staff to obtain prior authorizations is reduced by 70-90%, giving them time to focus more on engaging with their patients. 

Schedule a demo on www.infinx.com/request-a-demo to learn more today. 

Gartner, Hype Cycle for U.S. Healthcare Payers, 2023, 10 July 2023. Gartner and Hype Cycle are registered trademarks of Gartner, Inc. and/or its affiliates in the U.S. and internationally and are used herein with permission. All rights reserved. Gartner does not endorse any vendor, product or service depicted in its research publications, and does not advise technology users to select only those vendors with the highest ratings or other designation. Gartner research publications consist of the opinions of Gartner’s research organization and should not be construed as statements of fact. Gartner disclaims all warranties, expressed or implied, with respect to this research, including any warranties of merchantability or fitness for a particular purpose.

About Infinx Healthcare

Infinx Healthcare works closely with providers to overcome their revenue cycle challenges by leveraging automation and intelligence to increase reimbursements for patient care delivered. The technology platform optimizes the healthcare payment lifecycle by increasing reimbursements using AI, automation, analytics, integrations, and intelligent workforce management. Learn more at www.infinx.com.

Media Contact

Mark Macias

[email protected]

Contact Information:
Mark Macias
[email protected]


Original Source: Infinx Healthcare Recognized as a Sample Vendor for Intelligent Prior Authorization for Second Year in a Row in the Gartner Hype Cycle for U.S. Healthcare Payers, 2023

The Expendables 4 fires up $750k in Thursday previews

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The Expendables 4 fires up 0k in Thursday previews

The Expendables could be headed towards a $15 million opening weekend, putting in around the previous entry.

The Expendables 4 aka the incomprehensible Expend4bles took in $750,000 in previews on Thursday, indicating it could be headed towards a $15 million or so opening, according to sources.

Such an opening weekend would make it a tough mountain for The Expendables 4 to climb to recoup its $100 million budget. But if previous entries are any indication, it’s the international box office that will help it reach that goal. The previous outing, 2014’s The Expendables 3, opened with just under $16 million, peaking at #4 at the box office. Domestically, it would gross just $39 million, but the worldwide haul easily pushed it past $200 million, making it a global success. Still, it should be noted that The Expendables 3 had a Thursday take of $875,000.

The Expendables franchise has undoubtedly cooled. What started as a reunion of our favorite action heroes of the ‘80s and ‘90s – Stallone, Arnold, Dolph, Bruce, Chuck, Jean-Claude, and more – has devolved into what feels like direct-to-video territory. Gone are Schwarzenegger (despite being Netflix’s Chief Action Officer), Chuck Norris (who, now 83, hasn’t been in a movie since 2012’s The Expendables 2) and Jean-Claude Van Damme (hey, let the guy rest before Beetlejuice 2). Sure, Sylvester Stallone and Dolph Lundgren are there and Tony Jaa is generally fun to watch, but The Expendables 4 has apparently turned into the Jason Statham Show featuring 50 Cent, Megan Fox and Andy Garcia, some of whom are seen as expendable in other ways. And considering the third entry came out nearly a decade ago, The Expendables 4 is really looking at some dangerous, self-parodic territory.

The official plot of The Expendables 4: “Armed with every weapon they can get their hands on and the skills to use them, The Expendables are the world’s last line of defense and the team that gets called when all other options are off the table. But new team members with new styles and tactics are going to give “new blood” a whole new meaning.”

Will you be checking out The Expendables 4 this weekend? How do you think it will perform when its run has expired?

Originally published at https://www.joblo.com/the-expendables-4-fires-up-750k-in-thursday-previews/

The Exorcist: Believer promo centers on the characters Angela and Victor

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The Exorcist: Believer promo centers on the characters Angela and Victor

A new promo for director David Gordon Green’s The Exorcist: Believer shows a scene with the characters Angela and Victor

We’re exactly two weeks away from the October 6th theatrical release of director David Gordon Green‘s The Exorcist: Believer, and today a new promo has arrived online to give us a preview of a scene that features the characters Angela and Victor, played by Lidya Jewett (Nightbooks) and Leslie Odom Jr. (Hamilton). You can check it out in the embed above.

Green recently finished working on a trilogy of Halloween sequels for Universal and Blumhouse that consisted of Halloween (2018), Halloween Kills, and Halloween Ends. Now he’s working with the companies on a trilogy of sequels to The Exorcist (watch it HERE) that begins with Believer. Green crafted the story for the film with Danny McBride (who wrote all three of the new Halloweens with him) and their Halloween Kills co-writer Scott Teems, then wrote the screenplay with Peter Sattler (Broken Diamonds). Here’s the synopsis: Since the death of his pregnant wife in a Haitian earthquake 12 years ago, Victor Fielding has raised their daughter on his own. But when Angela and her friend Katherine, disappear in the woods, only to return three days later with no memory of what happened to them, it unleashes a chain of events that will force Victor to confront the nadir of evil and, in his terror and desperation, seek out the only person alive who has witnessed anything like it before: Chris MacNeil.

Ellen Burstyn reprises the role of Chris MacNeil, the character she played in the 1973 classic The Exorcist, “an actress who has been forever altered by what happened to her daughter Regan five decades before.” Odom, Jewett, and Burstyn are joined in the cast by newcomer Olivia O’Neill as Angela’s friend Katherine. Ann Dowd (The Handmaid’s Tale) plays Victor and Angela’s neighbor, and Jennifer Nettles (The Righteous Gemstones) and Norbert Leo Butz (Fosse/Verdon) play Katherine’s parents.

Okwui Okpokwasili (Master) is also in the cast, playing an unspecified role, and Raphael Sbarge (Carnosaur) plays a pastor. Original The Exorcist star Linda Blair is in there as well, reprising the role of Chris MacNeil’s daughter Regan.

The Exorcist: Believer is being produced by Jason Blum, David Robinson, and James Robinson. Green, Danny McBride, Stephanie Allain, and Couper Samuelson serve as executive producers. Ryan Turek is overseeing the project for Blumhouse.

Universal and Peacock forked over an amount somewhere in the range of $400 million to acquire the rights to distribute this trilogy, so you can understand why they’re trying to avoid competition. That’s a lot of money to recoup. It has already been announced that the next sequel, titled The Exorcist: Deceiver, will be reaching theatres on April 18, 2025.

What did you think of the The Exorcist: Believer Angela and Victor promo? Will you be watching this movie next month? Let us know by leaving a comment below.

Originally published at https://www.joblo.com/the-exorcist-believer-promo/

It Lives Inside Review

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It Lives Inside Review

Writer/Director Bishal Dutta uses a demon from Hindu mythology to tell a familiar story of trying to vanquish what cannot be stopped.

https://www.youtube.com/watch?v=flKY1xcUD5I

PLOT: An Indian-American teenager struggling with her cultural identity has a falling out with her former best friend and, in the process, unwittingly releases a demonic entity that grows stronger by feeding on her loneliness.

REVIEW: One of the coolest trends going on in horror right now is the usage of cultural Boogeymen. Some of these have reached the pop culture zenith, while others remain simple horrors for small-knit communities. Indian culture has a ton of demons, many of which the average American would have never heard anything about. The creature presented in It Lives Inside is called Pishacha and is based on flesh-eating demons in different Hindu and Buddhist mythologies. The history of the creature feels so much more intriguing since it’s based on actual mythology, versus something a screenwriter concocted to scare us. All of this is to say that, while the story may follow many beats we’ve seen before, It Lives Inside‘s unique identity makes it feel fresh and exciting.

Megan Suri’s Samidha is an extremely complex character that makes her intriguing to watch from the jump. I always love a story where we’re going down the rabbit hole of torture with a character. She doesn’t always do the right thing yet the justifications in the movie still keep the viewer firmly on her side. I also really enjoyed Tamira (Mohana Krishnan) as she serves as almost the Tina to Samidha’s Nancy. Which I think is apropos given some Nightmare on Elm Street imagery that the film evokes. I also like the dynamic that one of them is adapting to their new country while the other is struggling with it.

Written and directed by Bishal Dutta, he makes sure to bring some of his own personal experiences to the film, which grounds the film despite some of the otherworldly instances. The struggles with identity when moving to a new country, while still trying to pay respect to your heritage, is something many immigrants can relate to. 2023 has been an absolutely stellar year for cinematography in horror, and It Lives Inside continues that trend. Beautiful use of the wide aspect ratio and a color palate that only gets better as the film enters its final act make this stand out amongst other similar fare. There are several shots in this that I feel will be appearing in horror montages for years to come.

The demon itself is incredibly well done, utilizing mostly practical effects and being sure to keep them mostly in the shadows. The past year has had two similar villain reveals in both The Boogeyman and Smile, yet I’d say this eclipses both of those, by providing a great design that looks wonderful from all angles. It doesn’t matter how this is shot, it looks practical and, more importantly, great.  I’m very curious to see some more close-ups of this creature as there was plenty of detail to examine. If I had to get into what I didn’t like, it’s mostly the undefined rules with the creature. Whether it’s invisible or not seems mostly based on circumstance, which made it hard to establish tension. The creature’s presence felt like more of a roll of the dice. Thankfully, when it is around, it’s truly terrifying and leaves an impact. If anything, I could have gone for more violence from the creature. It’s supposed to be a flesh-eater after all but we’re mostly just treated to bites.

The story of It Lives Inside may be a bit generic, but its cultural roots really help to give it a unique identity. I often roll my eyes during the exposition scenes in films of this ilk yet I couldn’t get enough of Neeru Bajwa speaking on it with such authority. Megan Suri gives a phenomenal performance and the creature has one of the best designs in all of horror. The movie doesn’t tread any terribly new ground, but not all movies do. Sometimes a properly executed story with great performances and practical effects are all a good horror film needs.

it lives inside review

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Originally published at https://www.joblo.com/it-lives-inside-fantasia-review/

Seraxis to Provide Oral Update on Its Pancreatic Organoid Candidate for Functional Cure of T1D at the 59th Annual Meeting of the EASD

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Seraxis to Provide Oral Update on Its Pancreatic Organoid Candidate for Functional Cure of T1D at the 59th Annual Meeting of the EASD
Dr. William Rust will give an oral presentation on Seraxis’ proprietary technology for the production of therapeutic pancreatic organoids from pancreas-derived stem cells, as well as review initial diabetes model data of functional cure of Type 1 Diabetes. Seraxis’ presentation, entitled “Stem-cell Derived Islets for Treating Diabetes”, will be delivered in the session entitled "Transplantation of Islet and Stem Cells Today and Tomorrow".

Seraxis, Inc., a regenerative medicine company developing a pancreatic organoid cure to transform the lives of patients with Type 1 and insulin-requiring Type 2 diabetes, today announced that the European Association for the Study of Diabetes has selected Seraxis to present an oral discussion entitled “Stem-cell derived islets for Treating Diabetes” at the EASD 59th Annual Meeting in Hamburg. Seraxis CEO Dr. William Rust will be speaking in the 12:30-1:30 p.m. (CET) Short Oral Event A on Tuesday, October 3.

The accepted abstract summarizes Seraxis’ development of a novel human immortal stem cell line generated from a consented donor pancreas that differentiates to organoids resembling human islets in morphology, distribution and function of hormone expressing cells. In the mouse model of STZ induced Type 1 Diabetes, organoid implantation resulted in glycemic control 3-4 weeks post-implant. This is the first description of a novel, non-embryonic, non-iPSC cell bank with the potential for clinical benefit.

ABOUT SERAXIS

Seraxis is bringing transformative cures to millions of people worldwide struggling with the management and life-threatening complications of insulin-dependent diabetes. 

Seraxis’ lead program, SR-02, is a novel, off-the-shelf pancreatic organoid therapy slated to enter clinical testing with immunosuppressive therapy in 2024 in patients with severe recurrent hypoglycemia. A follow-on diabetes program, SR-03, is a version of the Seraxis organoid altered to be unrecognized by the immune system for the broader indication of insulin-dependent patients without chronic immune suppression.

Seraxis’ underlying proprietary technology enables the creation of a pipeline of novel stem cell-derived therapies originating from single donated organs for other indications. The company’s lead therapeutic program, SR-02, is manufactured from a stem cell line derived from a human donor pancreas. These cells preferentially re-differentiate into organoids containing all the endocrine cells of the native pancreatic islet, and with safety, potency, and manufacturing advantages over embryonic and induced pluripotent stem cells. 

Seraxis manufactures its best-in-class therapeutic organoids using scalable, clinically compliant processes in its cGMP facility located in Maryland’s I-270 Biotech Corridor. 

Contact:

Ted Hibben, Chief Corporate Development Officer

[email protected]

For more information, please visit www.seraxis.com.

Contact Information:
Ted Hibben
Chief Corporate Development Officer
[email protected]


Original Source: Seraxis to Provide Oral Update on Its Pancreatic Organoid Candidate for Functional Cure of T1D at the 59th Annual Meeting of the EASD